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Sunil A. David

Affiliations: 
Medicinal Chemistry University of Kansas, Lawrence, KS, United States 
Area:
Pharmaceutical Chemistry, Pharmacy, Immunology
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"Sunil David"
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Nikunj M. Shukla grad student 2011 University of Kansas
Hari Prasad Kokatla post-doc University of Kansas

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Publications

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Stickdorn J, Stein L, Arnold-Schild D, et al. (2022) Systemically Administered TLR7/8 Agonist and Antigen-Conjugated Nanogels Govern Immune Responses against Tumors. Acs Nano
Jangra S, De Vrieze J, Choi A, et al. (2021) Corrigendum: Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine. Angewandte Chemie (International Ed. in English). 60: 16741-16742
Huppertsberg A, Kaps L, Zhong Z, et al. (2021) Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators. Journal of the American Chemical Society
Li H, Van Herck S, Liu Y, et al. (2020) Imidazoquinoline-Conjugated Degradable Coacervate Conjugate for Local Cancer Immunotherapy. Acs Biomaterials Science & Engineering. 6: 4993-5000
Wang B, Van Herck S, Chen Y, et al. (2020) Prolonged innate immune activation by enzyme-sensitive imidazoquinoline TLR7/8 agonist prodrug vesicles. Journal of the American Chemical Society
Kockelmann J, Stickdorn J, Kasmi S, et al. (2020) Control over Imidazoquinoline Immune Stimulation by pH-Degradable Poly(norbornene) Nanogels. Biomacromolecules
De Vrieze J, Louage B, De Swarte K, et al. (2019) Potent lymphatic translocation and spatial control over innate immune activation by polymer-lipid amphiphile conjugates of small molecule TLR7/8 agonists. Angewandte Chemie (International Ed. in English)
Hu Z, Banothu J, Beesu M, et al. (2019) Identification of Human Toll-like Receptor 2-Agonistic Activity in Dihydropyridine-Quinolone Carboxamides. Acs Medicinal Chemistry Letters. 10: 132-136
De Vrieze J, Louage B, Deswarte K, et al. (2019) Amphiphile Polymer‐Lipidkonjugate zur potenten lymphatischen Anreicherung von TLR7/8‐Agonisten ermöglichen eine örtlich begrenzte Aktivierung des angeborenen Immunsystems Angewandte Chemie. 131: 15535-15541
Zhang Z, Ohto U, Shibata T, et al. (2018) Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands. Cell Reports. 25: 3371-3381.e5
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