Alexander C. Drohat

Affiliations: 
Biochemistry University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Biochemistry, Genetics
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"Alexander Drohat"
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Schnable BL, Schaich MA, Roginskaya V, et al. (2023) Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine. Biorxiv : the Preprint Server For Biology
Pidugu LS, Servius HW, Sevdalis SE, et al. (2023) Characterizing inhibitors of human AP endonuclease 1. Plos One. 18: e0280526
Servius HW, Pidugu LS, Sherman ME, et al. (2022) Rapid excision of oxidized adenine by human thymine DNA glycosylase. The Journal of Biological Chemistry. 299: 102756
Pidugu LS, Bright H, Lin WJ, et al. (2021) Structural Insights into the Mechanism of Base Excision by MBD4. Journal of Molecular Biology. 167097
DeNizio JE, Dow BJ, Serrano JC, et al. (2021) TET-TDG active DNA demethylation at CpG and non-CpG sites. Journal of Molecular Biology. 166877
Pidugu LS, Dai Q, Malik SS, et al. (2019) Excision of 5-carboxylcytosine by Thymine DNA Glycosylase. Journal of the American Chemical Society
Dow BJ, Malik SS, Drohat AC. (2019) Defining the Role of Nucleotide Flipping in Enzyme Specificity Using F NMR. Journal of the American Chemical Society
Yoluk O, Drohat AC, MacKerell AD. (2019) Elucidating Complimentary Base Specificity of Thymine DNA Glycosylase via Potential of Mean Force Molecular Dynamics Simulations Biophysical Journal. 116: 21a-22a
Tarantino ME, Dow BJ, Drohat AC, et al. (2018) Nucleosomes and the three glycosylases: High, medium, and low levels of excision by the uracil DNA glycosylase superfamily. Dna Repair
Coey CT, Drohat AC. (2018) Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase. Nucleic Acids Research
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