Rickey P. Hicks

Affiliations: 
Interdisciplinary Biological Sciences East Carolina University, Greenville, NC, United States 
Area:
Biochemistry
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"Rickey Hicks"
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Publications

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Hicks R. (2017) Preparation of Membrane Models of Gram-Negative Bacteria and Their Interaction with Antimicrobial Peptides Studied by CD and NMR. Methods in Molecular Biology (Clifton, N.J.). 1548: 231-245
Hicks RP. (2016) Antibacterial and anticancer activity of a series of novel peptides incorporating cyclic tetra-substituted C(α) amino acids. Bioorganic & Medicinal Chemistry
Abercrombie JJ, Leung KP, Chai H, et al. (2015) Spectral and biological evaluation of a synthetic antimicrobial peptide derived from 1-aminocyclohexane carboxylic acid. Bioorganic & Medicinal Chemistry. 23: 1341-7
Chai H, Allen WE, Hicks RP. (2014) Spectroscopic investigations of the binding mechanisms between antimicrobial peptides and membrane models of Pseudomonas aeruginosa and Klebsiella pneumoniae. Bioorganic & Medicinal Chemistry. 22: 4210-22
Bhonsle JB, Clark T, Bartolotti L, et al. (2013) A brief overview of antimicrobial peptides containing unnatural amino acids and ligand-based approaches for peptide ligands. Current Topics in Medicinal Chemistry. 13: 3205-24
Clark TD, Bartolotti L, Hicks RP. (2013) The application of DOSY NMR and molecular dynamics simulations to explore the mechanism(s) of micelle binding of antimicrobial peptides containing unnatural amino acids. Biopolymers. 99: 548-61
Hicks RP, Abercrombie JJ, Wong RK, et al. (2013) Antimicrobial peptides containing unnatural amino acid exhibit potent bactericidal activity against ESKAPE pathogens. Bioorganic & Medicinal Chemistry. 21: 205-14
Russell AL, Williams BC, Spuches A, et al. (2012) The effect of the length and flexibility of the side chain of basic amino acids on the binding of antimicrobial peptides to zwitterionic and anionic membrane model systems. Bioorganic & Medicinal Chemistry. 20: 1723-39
Hicks RP, Russell AL. (2012) Application of unnatural amino acids to the de novo design of selective antibiotic peptides. Methods in Molecular Biology (Clifton, N.J.). 794: 135-67
Russell AL, Spuches AM, Williams BC, et al. (2011) The effect of the placement and total charge of the basic amino acid clusters on antibacterial organism selectivity and potency. Bioorganic & Medicinal Chemistry. 19: 7008-22
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