Hemanta Baruah, Ph.D.
Affiliations: | 2005 | Wake Forest University, Winston-Salem, NC, United States |
Area:
Biochemistry, General Biophysics, OncologyGoogle:
"Hemanta Baruah"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Ulrich Bierbach | grad student | 2005 | Wake Forest | |
| (DNA interactions of a hybrid anticancer agent: A biophysical and high -resolution structural study.) | ||||
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Publications
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| Baruah H, Wright MW, Bierbach U. (2005) Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent. Biochemistry. 44: 6059-70 |
| Baruah H, Barry CG, Bierbach U. (2004) Platinum-intercalator conjugates: from DNA-targeted cisplatin derivatives to adenine binding complexes as potential modulators of gene regulation. Current Topics in Medicinal Chemistry. 4: 1537-49 |
| Baruah H, Day CS, Wright MW, et al. (2004) Metal-intercalator-mediated self-association and one-dimensional aggregation in the structure of the excised major DNA adduct of a platinum-acridine agent. Journal of the American Chemical Society. 126: 4492-3 |
| Baruah H, Bierbach U. (2004) Biophysical characterization and molecular modeling of the coordinative-intercalative DNA monoadduct of a platinum-acridinylthiourea agent in a site-specifically modified dodecamer. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 335-44 |
| Barry CG, Baruah H, Bierbach U. (2003) Unprecedented monofunctional metalation of adenine nucleobase in guanine- and thymine-containing dinucleotide sequences by a cytotoxic platinum-acridine hybrid agent. Journal of the American Chemical Society. 125: 9629-37 |
| Baruah H, Bierbach U. (2003) Unusual intercalation of acridin-9-ylthiourea into the 5'-GA/TC DNA base step from the minor groove: implications for the covalent DNA adduct profile of a novel platinum-intercalator conjugate. Nucleic Acids Research. 31: 4138-46 |
| Baruah H, Rector CL, Monnier SM, et al. (2002) Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates. Biochemical Pharmacology. 64: 191-200 |
| Baruah H, Rector CL, Monnier SM, et al. (2002) Erratum to “Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates” ☆: [Biochem. Pharmacol. 64 (2002) 191–200] Biochemical Pharmacology. 64: 751 |
| Martins ET, Baruah H, Kramarczyk J, et al. (2001) Design, synthesis, and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore. Journal of Medicinal Chemistry. 44: 4492-6 |