Jayati R. Choudhury, Ph.D.

Affiliations: 
2008 Wake Forest University, Winston-Salem, NC, United States 
Area:
Biochemistry, Molecular Biology, Oncology
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"Jayati Choudhury"
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Parents

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Ulrich Bierbach grad student 2008 Wake Forest
 (Biochemical and spectroscopic studies of DNA-targeted hybrid anticancer agents.)
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Publications

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Yoon JH, Basu D, Choudhury JR, et al. (2021) DNA Polymerase λ Promotes Error-free Replication through Watson-Crick Impairing N1-methyl-deoxyadenosine Adduct in Conjunction with DNA Polymerase ζ. The Journal of Biological Chemistry. 100868
Rechkoblit O, Choudhury JR, Buku A, et al. (2018) Structural basis for polymerase η-promoted resistance to the anticancer nucleoside analog cytarabine. Scientific Reports. 8: 12702
Jain R, Choudhury JR, Buku A, et al. (2017) Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι. Scientific Reports. 7: 43904
Gómez-Llorente Y, Malik R, Jain R, et al. (2013) The architecture of yeast DNA polymerase ζ. Cell Reports. 5: 79-86
Choudhury JR, Rao L, Bierbach U. (2011) Rates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 16: 373-80
Vasquez-Del Carpio R, Silverstein TD, Lone S, et al. (2009) Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. Plos One. 4: e5766
Ma Z, Choudhury JR, Wright MW, et al. (2008) A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer. Journal of Medicinal Chemistry. 51: 7574-80
Choudhury JR, Guddneppanavar R, Saluta G, et al. (2008) Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: effect of metal cis/trans isomerism and DNA threading groups. Journal of Medicinal Chemistry. 51: 3069-72
Guddneppanavar R, Choudhury JR, Kheradi AR, et al. (2007) Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity. Journal of Medicinal Chemistry. 50: 2259-63
Choudhury JR, Bierbach U. (2005) Characterization of the bisintercalative DNA binding mode of a bifunctional platinum-acridine agent. Nucleic Acids Research. 33: 5622-32
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