Gu Xiao, Ph.D.

Affiliations: 
2000 City University of New York, New York, NY, United States 
Area:
Molecular Biology
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"Gu Xiao"
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Parents

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Jill E. Bargonetti grad student 2000 CUNY
 (Studies of p53 -mediated mdm2 and gadd45 gene activation in nuclear chromatin.)
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Publications

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Lee R, Ellison V, Forbes D, et al. (2024) Chemokine CXCL12 Activates CXC Receptor 4 Metastasis Signaling Through the Upregulation of a CXCL12/CXCR4/MDMX (MDM4) Axis. Cancers. 16
Ellison V, Polotskaia A, Xiao G, et al. (2024) A CANCER PERSISTENT DNA REPAIR CIRCUIT DRIVEN BY MDM2, MDM4 (MDMX), AND MUTANT P53 FOR RECRUITMENT OF MDC1 AND 53BP1 TO CHROMATIN. Biorxiv : the Preprint Server For Biology
Madorsky Rowdo FP, Xiao G, Khramtsova GF, et al. (2024) Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment. Cancer Letters. 216608
Rowdo FPM, Xiao G, Khramtsova GF, et al. (2023) Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment. Biorxiv : the Preprint Server For Biology
Annor GK, Elshabassy N, Lundine D, et al. (2021) Oligomerization of Mutant p53 R273H is not Required for Gain-of-Function Chromatin Associated Activities. Frontiers in Cell and Developmental Biology. 9: 772315
Wilson T, Pirovano G, Xiao G, et al. (2021) PARP-Targeted Auger Therapy in p53 Mutant Colon Cancer Xenograft Mouse Models. Molecular Pharmaceutics
Ellison V, Annor GK, Freedman C, et al. (2021) Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity. Oncotarget. 12: 1128-1146
Xiao G, Annor GK, Fung K, et al. (2020) Targeting Triple Negative Breast Cancer with a Nucleus-Directed p53 Tetramerization Domain Peptide. Molecular Pharmaceutics
Kim JY, Lee R, Xiao G, et al. (2020) MDM2-C Functions as an E3 Ubiquitin Ligase. Cancer Management and Research. 12: 7715-7724
Xiao G, Lundine D, Annor GK, et al. (2019) Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer. Cancer Research
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