John Buynak
Affiliations: | Chemistry | Southern Methodist University, Dallas, TX, United States |
Area:
Organic ChemistryGoogle:
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Publications
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| Smith CA, Stewart NK, Toth M, et al. (2023) The C5α-Methyl-Substituted Carbapenem NA-1-157 Exhibits Potent Activity against spp. Isolates Producing OXA-48-Type Carbapenemases. Acs Infectious Diseases |
| Stewart NK, Toth M, Alqurafi MA, et al. (2022) C6 Hydroxymethyl-Substituted Carbapenem MA-1-206 Inhibits the Major Carbapenemase OXA-23 by Impeding Deacylation. Mbio. e0036722 |
| Gupta R, Al-Kharji NMSA, Alqurafi MA, et al. (2021) Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors. Acs Infectious Diseases |
| Lasarte-Monterrubio C, Vázquez-Ucha JC, Maneiro M, et al. (2021) Activity of Imipenem, Meropenem, Cefepime, and Sulbactam in Combination with the β-Lactamase Inhibitor LN-1-255 against spp. Antibiotics (Basel, Switzerland). 10 |
| Kang JS, Zhang AL, Faheem M, et al. (2018) Virtual Screening and Experimental Testing of B1 Metallo-β-lactamase Inhibitors. Journal of Chemical Information and Modeling |
| Vázquez-Ucha JC, Maneiro M, Martínez-Guitián M, et al. (2017) Activity of the β-Lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy |
| Nguyen TQ, Alqurafi M, Edwards C, et al. (2016) Functionalizing the γ-Position of α-Diazo-β-ketoesters. Tetrahedron Letters. 57: 3330-3333 |
| Vallejo JA, Martínez-Guitián M, Vázquez-Ucha JC, et al. (2016) LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48. The Journal of Antimicrobial Chemotherapy |
| Nguyen TQ, Alqurafi M, Edwards C, et al. (2016) Functionalizing the γ-position of α-diazo-β-ketoesters Tetrahedron Letters. 57: 3330-3333 |
| Oelschlaeger P, Aitha M, Yang H, et al. (2015) Meropenem and Chromacef Intermediates Observed in IMP-25 Metallo-β-Lactamase-Catalyzed Hydrolysis. Antimicrobial Agents and Chemotherapy. 59: 4326-30 |