Gopeekrishnan Sreenilayam, Ph.D.

Affiliations: 
2011 Chemistry University of Iowa, Iowa City, IA 
Area:
Pharmaceutical Chemistry, Organic Chemistry, Biochemistry
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"Gopeekrishnan Sreenilayam"
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Parents

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Gregory K. Friestad grad student 2011 University of Iowa
 (Asymmetric 1,5-polyol synthesis: A concise configuration-encoded approach.)
Rudi Fasan post-doc 2014- Rochester
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Publications

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Nam D, Tinoco A, Shen Z, et al. (2022) Enantioselective Synthesis of α-Trifluoromethyl Amines via Biocatalytic N-H Bond Insertion with Acceptor-Acceptor Carbene Donors. Journal of the American Chemical Society
Steck V, Sreenilayam G, Fasan R. (2020) Selective Functionalization of Aliphatic Amines via Myoglobin-catalyzed Carbene N-H Insertion. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 31: 224-229
Friedrich RM, Sreenilayam G, Hackbarth J, et al. (2018) Unified Strategy for 1,5,9- and 1,5,7-Triols via Configuration-Encoded 1,5-Polyol Synthesis: Enantioselective Preparation of γ-Sulfonyl-α-silyloxyaldehydes and Iterative Julia-Kocienski Coupling. The Journal of Organic Chemistry
Sreenilayam G, Moore EJ, Steck V, et al. (2017) Metal Substitution Modulates the Reactivity and Extends the Reaction Scope of Myoglobin Carbene Transfer Catalysts. Advanced Synthesis & Catalysis. 359: 2076-2089
Sreenilayam G, Moore EJ, Steck V, et al. (2017) Stereoselective olefin cyclopropanation under aerobic conditions with an artificial enzyme incorporating an iron-chlorin e6 cofactor. Acs Catalysis. 7: 7629-7633
Bajaj P, Sreenilayam G, Tyagi V, et al. (2016) Gram-Scale Synthesis of Chiral Cyclopropane-Containing Drugs and Drug Precursors with Engineered Myoglobin Catalysts Featuring Complementary Stereoselectivity. Angewandte Chemie (International Ed. in English)
Tyagi V, Sreenilayam G, Bajaj P, et al. (2016) Biocatalytic Synthesis of Allylic and Allenyl Sulfides through a Myoglobin-Catalyzed Doyle-Kirmse Reaction. Angewandte Chemie (International Ed. in English)
Sreenilayam G, Fasan R. (2015) Correction: Myoglobin-catalyzed intermolecular carbene N-H insertion with arylamine substrates. Chemical Communications (Cambridge, England). 51: 1744
Sreenilayam G, Fasan R. (2015) Myoglobin-catalyzed intermolecular carbene N-H insertion with arylamine substrates. Chemical Communications (Cambridge, England). 51: 1532-4
Friestad GK, Sreenilayam G, Cannistra JC, et al. (2012) Preparation of enol ester epoxides and their ring-opening to α-silyloxyaldehydes Tetrahedron Letters. 53: 5064-5067
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