Andrew T. Koppisch, Ph.D.

Affiliations: 
2002 University of Utah, Salt Lake City, UT 
Area:
Biochemistry, Organic Chemistry
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C. Dale Poulter grad student 2002 University of Utah
 (Enzymatic characterization of Escherichia coli methylerythritol phosphate synthase and synthesis of methylerythritol phosphate pathway metabolites.)
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Publications

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Greene JR, Merrett KL, Heyert AJ, et al. (2019) Scope and efficacy of the broad-spectrum topical antiseptic choline geranate. Plos One. 14: e0222211
Bartee D, Sanders S, Phillips PD, et al. (2019) Enamide Prodrugs of Acetyl Phosphonate DXP Synthase Inhibitors as Potent Antibacterial Agents. Acs Infectious Diseases
Sanders S, Bartee D, Harrison MJ, et al. (2018) Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors. Plos One. 13: e0197638
Sanders S, Vierling RJ, Bartee D, et al. (2017) Challenges and Hallmarks of Establishing Alkylacetylphosphonates as Probes of Bacterial 1-Deoxy-d-xylulose 5-Phosphate Synthase. Acs Infectious Diseases
Harrington L, Jha RK, Kern TL, et al. (2016) Rapid thermostabilization of Bacillus thuringiensis serovar konkukian 97-27 dehydroshikimate dehydratase through a structure-based enzyme design and whole cell activity assay. Acs Synthetic Biology
Jarchow-Choy SK, Koppisch AT, Fox DT. (2014) Synthetic Routes to Methylerythritol Phosphate Pathway Intermediates and Downstream Isoprenoids. Current Organic Chemistry. 18: 1050-1072
Fox DT, Schmidt EN, Tian H, et al. (2014) Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2. Plos One. 9: e95271
Stone JK, Heiss C, Wang Z, et al. (2014) Structural characterization of polysaccharides expressed by Burkholderia oklahomensis E0147. Carbohydrate Research. 386: 68-72
Smith JM, Warrington NV, Vierling RJ, et al. (2014) Targeting DXP synthase in human pathogens: enzyme inhibition and antimicrobial activity of butylacetylphosphonate. The Journal of Antibiotics. 67: 77-83
Fox DT, Hotta K, Kim CY, et al. (2008) The missing link in petrobactin biosynthesis: asbF encodes a (-)-3-dehydroshikimate dehydratase. Biochemistry. 47: 12251-3
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