Keriann M. Oertell, Ph.D.
Affiliations: | 2013 | Chemistry | University of Southern California, Los Angeles, CA, United States |
Area:
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"Keriann Oertell"Mean distance: (not calculated yet)
Parents
Sign in to add mentorMyron Goodman | grad student | 2013 | USC | |
(DNA polymerase mechanism and fidelity: Using beta,gamma-bridging oxygen substituted dNTPs to study the mechanism of DNA polymerase beta.) |
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Publications
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Oertell K, Florian J, Haratipour P, et al. (2019) A Transition-State Perspective on Y-Family DNA Polymerase η Fidelity in Comparison with X-Family DNA Polymerases λ and β. Biochemistry |
Oertell K, Kashemirov BA, Negahbani A, et al. (2018) Probing DNA base-dependent leaving group kinetic effects on the DNA polymerase transition state. Biochemistry |
Batra VK, Oertell K, Beard WA, et al. (2018) Mapping functional substrate-enzyme interactions in the pol β active site through chemical biology: Structural responses to acidity modification of incoming dNTPs. Biochemistry |
Oertell K, Harcourt EM, Mohsen MG, et al. (2016) Kinetic selection vs. free energy of DNA base pairing in control of polymerase fidelity. Proceedings of the National Academy of Sciences of the United States of America |
Kadina AP, Kashemirov BA, Oertell K, et al. (2015) Two Scaffolds from Two Flips: (α,β)/(β,γ) CH2/NH "Met-Im" Analogues of dTTP. Organic Letters. 17: 2586-9 |
Shakhmin A, Jones JP, Bychinskaya I, et al. (2014) Preparation of fluorinated RNA nucleotide analogs potentially stable to enzymatic hydrolysis in RNA and DNA polymerase assays. Journal of Fluorine Chemistry. 167: 226-230 |
Oertell K, Chamberlain BT, Wu Y, et al. (2014) Transition state in DNA polymerase β catalysis: rate-limiting chemistry altered by base-pair configuration. Biochemistry. 53: 1842-8 |
Shakhmin A, Jones JP, Bychinskaya I, et al. (2014) Preparation of fluorinated RNA nucleotide analogs potentially stable to enzymatic hydrolysis in RNA and DNA polymerase assays Journal of Fluorine Chemistry |
Oertell K, Wu Y, Zakharova VM, et al. (2012) Effect of β,γ-CHF- and β,γ-CHCl-dGTP halogen atom stereochemistry on the transition state of DNA polymerase β. Biochemistry. 51: 8491-501 |
Surya Prakash GK, Zibinsky M, Upton TG, et al. (2010) Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Proceedings of the National Academy of Sciences of the United States of America. 107: 15693-8 |