Focco van den Akker
Affiliations: | 2003- | Biochemistry | Case Western Reserve University, Cleveland Heights, OH, United States |
Area:
BiochemistryWebsite:
http://www.cwru.edu/med/biochemistry/faculty/vandenakker.htmlGoogle:
"Focco van den Akker"Bio:
http://nitricoxidesociety.org/conferences/2014/?page_id=480
https://books.google.com/books?id=5YcvAQAAIAAJ
Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Wilhelmus G.J. Hol | grad student | 1997 | University of Washington | |
| (X-ray crystallographic studies of heat-labile enterotoxins from Escherichia coli.) | ||||
| George R. Stark | post-doc | 2000 | Cleveland Clinic | |
Children
Sign in to add trainee| Jared Sampson | research assistant | 2005-2008 | Case Western Medical School |
| Tahani Alsenani | grad student | 2019- | Case Western |
| Xiaolei Ma | grad student | 2003-2008 | Case Western |
| Wei Ke | grad student | 2011 | Case Western |
| Elizabeth Rodkey | grad student | 2007-2012 | Case Western |
| Jagamya Vijayaraghavan | grad student | 2010-2016 | Case Western |
| Vijay Kumar | post-doc | 2008- | Case Western |
| Malligarjunan Rajavel | post-doc | 2019- | Case Western |
| Know-Peng Ng | post-doc | 2000-2003 | Cleveland Clinic Foundation |
| Priyaranjan Pattanaik | post-doc | 2003-2008 | Case Western |
| Faye Martin | post-doc | 2009-2010 | Case Western |
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Publications
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| Mack AR, Kumar V, Taracila MA, et al. (2023) Natural protein engineering in the Ω-loop: the role of Y221 in ceftazidime and ceftolozane resistance in -derived cephalosporinase. Antimicrobial Agents and Chemotherapy. e0079123 |
| Kumar V, Boorman J, Greenlee WJ, et al. (2023) Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds. Protein Science : a Publication of the Protein Society. e4683 |
| Zhou HL, Hausladen A, Anand P, et al. (2023) Identification of a Selective SCoR2 Inhibitor That Protects Against Acute Kidney Injury. Journal of Medicinal Chemistry |
| Alsenani TA, Rodríguez MM, Ghiglione B, et al. (2023) Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses. Antimicrobial Agents and Chemotherapy. e0093022 |
| Taracila MA, Bethel CR, Hujer AM, et al. (2022) Different Conformations Revealed by NMR Underlie Resistance to Ceftazidime/Avibactam and Susceptibility to Meropenem and Imipenem among D179Y Variants of KPC β-Lactamase. Antimicrobial Agents and Chemotherapy. e0212421 |
| Kumar V, Viviani SL, Ismail J, et al. (2021) Structural analysis of the boronic acid β-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3. Plos One. 16: e0258359 |
| Goldberg JA, Kumar V, Spencer EJ, et al. (2021) A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp. European Journal of Medicinal Chemistry. 220: 113436 |
| Hahn MG, Lampe T, El Sheikh S, et al. (2021) Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042). Journal of Medicinal Chemistry |
| Kumar V, Mathure SA, Lee M, et al. (2021) Turnover Chemistry and Structural Characterization of the Cj0843c Lytic Transglycosylase of . Biochemistry |
| Rajavel M, Kumar V, Nguyen H, et al. (2021) Structural Characterization of Diazabicyclooctane β-Lactam "Enhancers" in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa. Mbio. 12 |