Garold S. Yost

Affiliations: 
Pharmacology and Toxicology University of Utah, Salt Lake City, UT 
Area:
Toxicology, General Biophysics, Biochemistry
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Roberts JK, Moore CD, Romero EG, et al. (2013) Regulation of CYP3A genes by glucocorticoids in human lung cells. F1000research. 2: 173
Roberts JK, Moore CD, Ward RM, et al. (2013) Metabolism of beclomethasone dipropionate by cytochrome P450 3A enzymes. The Journal of Pharmacology and Experimental Therapeutics. 345: 308-16
Cruzan G, Bus J, Hotchkiss J, et al. (2013) Studies of styrene, styrene oxide and 4-hydroxystyrene toxicity in CYP2F2 knockout and CYP2F1 humanized mice support lack of human relevance for mouse lung tumors. Regulatory Toxicology and Pharmacology : Rtp. 66: 24-9
Moore CD, Roberts JK, Orton CR, et al. (2013) Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 379-89
Reilly CA, Henion F, Bugni TS, et al. (2013) Reactive intermediates produced from the metabolism of the vanilloid ring of capsaicinoids by p450 enzymes. Chemical Research in Toxicology. 26: 55-66
Shahrokh K, Cheatham TE, Yost GS. (2012) Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen. Biochimica Et Biophysica Acta. 1820: 1605-17
Zhou X, D'Agostino J, Li L, et al. (2012) Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 642-7
Deering-Rice CE, Johansen ME, Roberts JK, et al. (2012) Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material. Molecular Pharmacology. 81: 411-9
Shahrokh K, Orendt A, Yost GS, et al. (2012) Quantum mechanically derived AMBER-compatible heme parameters for various states of the cytochrome P450 catalytic cycle. Journal of Computational Chemistry. 33: 119-33
Thomas KC, Roberts JK, Deering-Rice CE, et al. (2012) Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L111-9
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