Alexei Degterev
Affiliations: | Biochemistry | Sackler School of Graduate Biomedical Sciences (Tufts University) |
Area:
Biochemistry, Cell Biology, Molecular BiologyGoogle:
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| Jetton D, Muendlein HI, Connolly WM, et al. (2024) Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection. Cell Reports. 43: 114641 |
| Vitale I, Pietrocola F, Guilbaud E, et al. (2023) Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation |
| Johnson JL, Yaron TM, Huntsman EM, et al. (2023) An atlas of substrate specificities for the human serine/threonine kinome. Nature |
| Delanghe T, Huyghe J, Lee S, et al. (2021) Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor. Cell Death & Disease. 12: 699 |
| Zelic M, Pontarelli F, Woodworth L, et al. (2021) RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis. Cell Reports. 35: 109112 |
| Nikhar S, Siokas I, Schlicher L, et al. (2021) Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling. European Journal of Medicinal Chemistry. 215: 113252 |
| Muendlein HI, Connolly WM, Magri Z, et al. (2021) ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1. Nature Communications. 12: 86 |
| Lule S, Wu L, Sarro-Schwartz A, et al. (2020) Cell-specific activation of RIPK1 and MLKL after intracerebral hemorrhage in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20973609 |
| Cuny GD, Degterev A. (2020) RIPK protein kinase family: Atypical lives of typical kinases. Seminars in Cell & Developmental Biology |
| Suebsuwong C, Dai B, Pinkas DM, et al. (2020) Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. European Journal of Medicinal Chemistry. 200: 112417 |