Clint Mitchell, Ph.D.
Affiliations: | 2006 | Virginia Commonwealth University, Richmond, VA, United States |
Area:
Oncology, Molecular Biology, Biomedical EngineeringGoogle:
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Zhang G, Park MA, Mitchell C, et al. (2016) Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling. The Journal of Biological Chemistry. 291: 20823 |
Klionsky DJ, Abdelmohsen K, Abe A, et al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222 |
Das A, Durrant D, Mitchell C, et al. (2015) Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95. Oncotarget |
Mitchell C, Hamed HA, Cruickshanks N, et al. (2011) Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death. Cancer Biology & Therapy. 12: 215-28 |
Park MA, Hamed HA, Mitchell C, et al. (2011) A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels. Molecular Pharmacology. 79: 368-80 |
Hamed HA, Mitchell C, Dent P, et al. (2011) Abstract 5383: Inhibition of MCL-1 in mammary and CNS tumor cells promotes cell deathin vitroandin vivo Cancer Research. 71: 5383-5383 |
Das A, Durrant D, Mitchell C, et al. (2010) Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 107: 18202-7 |
Mitchell C, Yacoub A, Hossein H, et al. (2010) Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo. Cancer Biology & Therapy. 10: 903-17 |
Mitchell C, Park M, Eulitt P, et al. (2010) Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells. Molecular Pharmacology. 78: 909-17 |
Park MA, Mitchell C, Zhang G, et al. (2010) Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway. Cancer Research. 70: 6313-24 |