Aditi P. Martin, Ph.D.

Affiliations: 
2009 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Oncology
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Paul Dent grad student 2009 VCU
 (Therapeutic drugs in cancer and resistance.)
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Publications

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Mitchell C, Yacoub A, Hossein H, et al. (2010) Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo. Cancer Biology & Therapy. 10: 903-17
Martin AP, Mitchell C, Rahmani M, et al. (2009) Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy. Cancer Biology & Therapy. 8: 2084-96
Dahan S, Roth-Walter F, Martin AP, et al. (2009) Lymphoepithelial interactions: a new paradigm. Annals of the New York Academy of Sciences. 1165: 323-6
Martin AP, Park MA, Mitchell C, et al. (2009) BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing. Molecular Pharmacology. 76: 327-41
Park MA, Walker T, Martin AP, et al. (2009) MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism. Molecular Cancer Therapeutics. 8: 1280-91
Park MA, Zhang G, Martin AP, et al. (2008) Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. Cancer Biology & Therapy. 7: 1648-62
Zhang G, Park MA, Mitchell C, et al. (2008) Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5385-99
Martin AP, Miller A, Emad L, et al. (2008) Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation. Molecular Pharmacology. 74: 807-22
Hamed H, Mitchell C, Park MA, et al. (2008) Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo. Cancer Biology & Therapy. 7: 587-93
Grisotto MG, Garin A, Martin AP, et al. (2006) The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells. The Journal of Clinical Investigation. 116: 1264-73
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