Sven M. Guenther, Ph.D.

Affiliations: 
2003 University of Iowa, Iowa City, IA 
Area:
Organic Chemistry, Pharmaceutical Chemistry, Pharmacology
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"Sven Guenther"
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Vasu Nair grad student 2003 University of Iowa
 (Molecular design and synthesis of potential antiviral isonucleosides.)
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Publications

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Shammas H, Kloster Fog C, Klein P, et al. (2025) Mechanistic insights into arimoclomol mediated effects on lysosomal function in Niemann-pick type C disease. Molecular Genetics and Metabolism. 145: 109103
Braeckman R, Guenther S, Mickle TC, et al. (2022) Dose Proportionality and Steady-State Pharmacokinetics of Serdexmethylphenidate/Dexmethylphenidate, a Novel Prodrug Combination to Treat Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology
Shram MJ, Setnik B, Webster L, et al. (2022) Oral, intranasal, and intravenous abuse potential of serdexmethylphenidate, a novel prodrug of d-methylphenidate. Current Medical Research and Opinion. 1-40
Kollins SH, Braeckman R, Guenther S, et al. (2021) A Randomized, Controlled Laboratory Classroom Study of Serdexmethylphenidate and d-Methylphenidate Capsules in Children with Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology
Guenther S, Mickle TC, Barrett AC, et al. (2019) Pharmacokinetics and Abuse Potential of Asalhydromorphone, a Novel Prodrug of Hydromorphone, After Intranasal Administration in Recreational Drug Users. Pain Medicine (Malden, Mass.)
Mickle TC, Guenther SM, Barrett AC, et al. (2017) Pharmacokinetics and Abuse Potential of Benzhydrocodone, a Novel Prodrug of Hydrocodone, After Intranasal Administration in Recreational Drug Users. Pain Medicine (Malden, Mass.)
Guenther SM, Mickle TC, Barrett AC, et al. (2017) Relative Bioavailability, Intranasal Abuse Potential, and Safety of Benzhydrocodone/Acetaminophen Compared with Hydrocodone Bitartrate/Acetaminophen in Recreational Drug Abusers. Pain Medicine (Malden, Mass.)
Cassidy TA, Oyedele N, Mickle TC, et al. (2017) Patterns of abuse and routes of administration for immediate-release hydrocodone combination products. Pharmacoepidemiology and Drug Safety
Guenther S, Nair V. (2004) A new approach for the synthesis of novel 5-substituted isodeoxyuridine analogs. Nucleosides, Nucleotides & Nucleic Acids. 23: 183-93
Guenther S, Balzarini J, De Clercq E, et al. (2002) A thymidine phosphorylase-stable analogue of BVDU with significant antiviral activity. Journal of Medicinal Chemistry. 45: 5426-9
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