Robert T. Dorsam, Ph.D.
Affiliations: | 2004 | Temple University, Philadelphia, PA, United States |
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Sign in to add mentor| Satya P. Kunapuli | grad student | 2004 | Temple University | |
| (The interplay of G protein-coupled signaling pathways in platelet activation.) | ||||
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| Vaqué JP, Dorsam RT, Feng X, et al. (2013) A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors. Molecular Cell. 49: 94-108 |
| Bhavaraju K, Lakhani PR, Dorsam RT, et al. (2011) G(12/13) signaling pathways substitute for integrin αIIbβ3-signaling for thromboxane generation in platelets. Plos One. 6: e16586 |
| Kahner BN, Dorsam RT, Kim S, et al. (2008) Hematopoietic lineage cell-specific protein-1 (HS1) regulates PAR-mediated ERK activation and thromboxane generation in platelets. Platelets. 19: 614-23 |
| Kahner BN, Dorsam RT, Kunapuli SP. (2008) Role of P2Y receptor subtypes in platelet-derived microparticle generation. Frontiers in Bioscience : a Journal and Virtual Library. 13: 433-9 |
| Kahner BN, Dorsam RT, Mada SR, et al. (2007) Hematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation. Blood. 110: 2449-56 |
| Garcia A, Quinton TM, Dorsam RT, et al. (2005) Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets. Blood. 106: 3410-4 |
| Murugappan S, Shankar H, Bhamidipati S, et al. (2005) Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets. Blood. 106: 550-7 |
| Dorsam RT, Kim S, Murugappan S, et al. (2005) Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways. Blood. 105: 2749-56 |
| Dorsam RT, Tuluc M, Kunapuli SP. (2004) Role of protease-activated and ADP receptor subtypes in thrombin generation on human platelets. Journal of Thrombosis and Haemostasis : Jth. 2: 804-12 |
| Dorsam RT, Kunapuli SP. (2004) Central role of the P2Y12 receptor in platelet activation. The Journal of Clinical Investigation. 113: 340-5 |