Mark J. Mitton-Fry, Ph.D.
Affiliations: | 2002 | University of Colorado, Boulder, Boulder, CO, United States |
Area:
Organic Chemistry, Pharmaceutical ChemistryGoogle:
"Mark Mitton-Fry"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Tarek H Sammakia | grad student | 2002 | CU Boulder | |
| (Strategies for the synthesis of the oxo polyene macrolide antibiotics. Application to the total synthesis of RK-397 and dermostatin A.) | ||||
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Publications
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| West JS, Mann CA, Mitton-Fry MJ. (2025) Decagram-Scale Synthesis of the Novel Bacterial Topoisomerase Inhibitor OSUAB-0284. Organic Process Research & Development. 29: 1136-1151 |
| Powell JW, Mann CA, Toth PD, et al. (2024) Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening. Acs Medicinal Chemistry Letters. 15: 1287-1297 |
| Phelps HA, Kuhn M, Lu Y, et al. (2023) Antibacterial activity of novel bacterial topoisomerase inhibitors against key veterinary pathogens. Veterinary Microbiology. 284: 109840 |
| Mohammed S, West JS, Mitton-Fry MJ. (2022) Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds. Synopen (2017). 6: 110-131 |
| Lu Y, Vibhute S, Li L, et al. (2021) Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with Efficacy against MRSA. Journal of Medicinal Chemistry |
| Lu Y, Papa JL, Nolan S, et al. (2020) Dioxane-Linked Amide Derivatives as Novel Bacterial Topoisomerase Inhibitors against Gram-Positive . Acs Medicinal Chemistry Letters. 11: 2446-2454 |
| Okumu A, Lu Y, Dellos-Nolan S, et al. (2020) Novel bacterial topoisomerase inhibitors derived from isomannide. European Journal of Medicinal Chemistry. 199: 112324 |
| Li L, Okumu AA, Nolan S, et al. (2019) 1,3-Dioxane-linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced hERG Inhibition. Acs Infectious Diseases |
| Li L, Okumu A, Dellos-Nolan S, et al. (2018) Synthesis and anti-staphylococcal activity of novel bacterial topoisomerase inhibitors with a 5-amino-1,3-dioxane linker moiety. Bioorganic & Medicinal Chemistry Letters |
| Vazquez ML, Kaila N, Strohbach JW, et al. (2018) Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry |