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Michal R. Szymanski, Ph.D.

Affiliations: 
2011 University of Texas Medical Branch, Galveston, TX 
Area:
Medical Biophysics, Biochemistry
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"Michal Szymanski"
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Wlodek Bujalowski grad student 2011 UTMB
 (Helicase-Initiated Assembly of Macromolecular Machines Involved in DNA Replication.)

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Publications

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Szymanski MR, Karlowicz A, Herrmann GK, et al. (2022) Human EXOG Possesses Strong AP Hydrolysis Activity: Implication on Mitochondrial DNA Base Excision Repair. Journal of the American Chemical Society. 144: 23543-23550
Szymanski MR, Yu W, Gmyrek AM, et al. (2017) A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease. Nature Communications. 8: 14959
Li M, Mislak AC, Foli Y, et al. (2016) DNA Polymerase-γ R953C Mutant is Associated with ART-Induced Mitochondrial Toxicity. Antimicrobial Agents and Chemotherapy
Sohl CD, Szymanski MR, Mislak AC, et al. (2016) Erratum: Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ (Proceedings of the National Academy of Sciences of the United States of America (2015) 112 (8596-8601) DOI: 10.1073/pnas.1421733112) Proceedings of the National Academy of Sciences of the United States of America. 113
Sohl CD, Szymanski MR, Mislak AC, et al. (2015) Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ. Proceedings of the National Academy of Sciences of the United States of America. 112: 8596-601
Szymanski MR, Kuznetsov VB, Shumate C, et al. (2015) Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase. The Embo Journal. 34: 1959-70
Szymanski MR, Jezewska MJ, Bujalowski W. (2013) Energetics of the Escherichia coli DnaT protein trimerization reaction. Biochemistry. 52: 1858-73
Szymanski MR, Jezewska MJ, Bujalowski W. (2013) The Escherichia coli primosomal DnaT protein exists in solution as a monomer-trimer equilibrium system. Biochemistry. 52: 1845-57
Szymanski MR, Jezewska MJ, Bujalowski WM. (2013) Unraveling the Mechanism of the Primosome Assembly Process Biophysical Journal. 104: 253a
Szymanski MR, Jezewska MJ, Bujalowski W. (2012) Helicase-Initiated Assembly of the Primosome Biophysical Journal. 102: 486a
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