Natalie Lassen, Ph.D.

Affiliations: 
2006 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Molecular Biology, Toxicology
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Vasilis Vasiliou grad student 2006 University of Colorado, Denver
 (Roles of aldehyde dehydrogenases (ALDHs) against oxidative stress.)
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Publications

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Black W, Chen Y, Matsumoto A, et al. (2012) Molecular mechanisms of ALDH3A1-mediated cellular protection against 4-hydroxy-2-nonenal. Free Radical Biology & Medicine. 52: 1937-44
Brocker C, Lassen N, Estey T, et al. (2010) Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress. The Journal of Biological Chemistry. 285: 18452-63
Su Y, Cortez C, Yeh S, et al. (2010) Evaluation of MultiParameter Biomarker set for Oxidative Stress Assessment Free Radical Biology and Medicine. 49: S171-S172
D'Amelio S, Lassen N, Vasiliou V, et al. (2009) Duane retraction syndrome, nystagmus, retinal pigment epitheliopathy and epiretinal membrane with micro- and pachygyria, developmental delay, hearing loss and craniopharyngioma. Ophthalmic Genetics. 30: 7-12
Lassen N, Black WJ, Estey T, et al. (2008) The role of corneal crystallins in the cellular defense mechanisms against oxidative stress. Seminars in Cell & Developmental Biology. 19: 100-12
Lassen N, Bateman JB, Estey T, et al. (2007) Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice. The Journal of Biological Chemistry. 282: 25668-76
Estey T, Piatigorsky J, Lassen N, et al. (2007) ALDH3A1: a corneal crystallin with diverse functions. Experimental Eye Research. 84: 3-12
Lassen N, Pappa A, Black WJ, et al. (2006) Antioxidant function of corneal ALDH3A1 in cultured stromal fibroblasts. Free Radical Biology & Medicine. 41: 1459-69
Bhave SV, Hoffman PL, Lassen N, et al. (2006) Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice. Alcoholism, Clinical and Experimental Research. 30: 1659-69
Muzio G, Trombetta A, Maggiora M, et al. (2006) Arachidonic acid suppresses growth of human lung tumor A549 cells through down-regulation of ALDH3A1 expression. Free Radical Biology & Medicine. 40: 1929-38
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