Jose A. Ospina, Ph.D.

Affiliations: 
2003 University of California, Irvine, Irvine, CA 
Area:
Pharmacology, Animal Physiology Biology, Neuroscience Biology
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"Jose Ospina"
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Sue P. Duckles grad student 2003 UC Irvine
 (Estrogen regulation of prostanoid pathways in the cerebral circulation.)
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Ospina JA, Brevig HN, Krause DN, et al. (2004) Estrogen suppresses IL-1beta-mediated induction of COX-2 pathway in rat cerebral blood vessels. American Journal of Physiology. Heart and Circulatory Physiology. 286: H2010-9
Ospina JA, Duckles SP, Krause DN. (2003) 17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation. American Journal of Physiology. Heart and Circulatory Physiology. 285: H241-50
Ospina JA, Krause DN, Duckles SP. (2002) 17beta-estradiol increases rat cerebrovascular prostacyclin synthesis by elevating cyclooxygenase-1 and prostacyclin synthase. Stroke; a Journal of Cerebral Circulation. 33: 600-5
Krause DN, Geary GG, McNeill AM, et al. (2002) Impact of hormones on the regulation of cerebral vascular tone International Congress Series. 1235: 395-399
Geary GG, McNeill AM, Ospina JA, et al. (2001) Selected contribution: cerebrovascular nos and cyclooxygenase are unaffected by estrogen in mice lacking estrogen receptor-alpha. Journal of Applied Physiology (Bethesda, Md. : 1985). 91: 2391-9; discussion 2
Geary GG, Mcneill AM, Ospina JA, et al. (2001) Genome and hormones: Gender differences in physiology selected contribution: Cerebrovascular NOS and cyclooxygenase are unaffected by estrogen in mice lacking estrogen receptor-α Journal of Applied Physiology. 91: 2391-2399
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