Joshua C. Canzoneri, Ph.D.

Affiliations: 
2012 Chemistry and Biochemistry Georgia Institute of Technology, Atlanta, GA 
Area:
Pharmaceutical Chemistry, Biochemistry, Physical Chemistry
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"Joshua Canzoneri"
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Parents

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Adegboyega K. Oyelere grad student 2012 Georgia Tech
 (Interaction of small molecules with nucleic acid targets: From RNA secondary structure to the ribosome.)
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Publications

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Zhu B, Lindsey A, Li N, et al. (2017) Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling. Oncotarget. 8: 69264-69280
Abdel-Rahman HM, Abdel-Aziz M, Tinsley HN, et al. (2016) Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors. Archiv Der Pharmazie. 349: 104-11
Keeton AB, Zhu B, Lee KJ, et al. (2016) Abstract 326: Discovery and in vitro and in vivo characterization of a novel, small-molecule Ras inhibitor class Cancer Research. 76: 326-326
Elhady AK, Sigler SC, Noureldin N, et al. (2015) Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors. Scientia Pharmaceutica. 84: 428-446
Hassaan EA, Sigler SC, Ibrahim TM, et al. (2015) Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach. Medicinal Chemistry (Shariqah (United Arab Emirates))
Li N, Chen X, Zhu B, et al. (2015) Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10. Oncotarget
Li N, Lee K, Xi Y, et al. (2015) Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity. Oncogene. 34: 1499-509
Li N, Chen X, Zhu B, et al. (2015) Suppression of ß-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10 Oncotarget. 6: 27403-27415
Canzoneri JC, Chen X, Keeton AB, et al. (2015) Abstract 701: A novel class of Ras selective inhibitors Cancer Research. 75: 701-701
Washington AZ, Benicewicz DB, Canzoneri JC, et al. (2014) Macrolide-peptide conjugates as probes of the path of travel of the nascent peptides through the ribosome. Acs Chemical Biology. 9: 2621-31
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