Stephen G. Aller, Ph.D.

Affiliations: 
2001-2006 Molecular Biophysics & Biochemistry Yale University, New Haven, CT 
 2009- Pharmacology & Toxicology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
General Biophysics, Biochemistry, Molecular Biology, Cell Biology, Structural Biology
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"Stephen Aller"
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Vinzenz M. Unger grad student 2006 Yale
 (Insights into the molecular structure of copper uptake in eukaryotes.)
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Publications

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Martin CL, Chester DW, Radka CD, et al. (2023) Structures of the Insecticidal Toxin Complex Subunit XptA2 Highlight Roles for Flexible Domains. International Journal of Molecular Sciences. 24
Aller SG, Segrest JP. (2022) The regulatory domains of the lipid exporter ABCA1 form domain swapped latches. Plos One. 17: e0262746
Radka CD, Aller SG. (2021) Site 2 of the Yersinia pestis substrate-binding protein YfeA is a dynamic surface metal-binding site. Acta Crystallographica. Section F, Structural Biology Communications. 77: 286-293
Thomas C, Aller SG, Beis K, et al. (2020) Structural and functional diversity calls for a new classification of ABC transporters. Febs Letters
Le CA, Harvey DS, Aller SG. (2020) Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj. 7: 663-672
Doiron JE, Le CA, Bacsa J, et al. (2020) Structural Consequences of the 1,2,3-Triazole as an Amide Bioisostere in Analogs of Cystic Fibrosis Drugs VX-809 and VX-770. Chemmedchem
Radka CD, Labiuk SL, DeLucas LJ, et al. (2019) Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms. Acta Crystallographica. Section D, Structural Biology. 75: 831-840
Doiron JE, Le CA, Ody BK, et al. (2019) Evaluation of 1,2,3-Triazoles as Amide Bioisosteres In Cystic Fibrosis Transmembrane Conductance Regulator Modulators VX-770 and VX-809. Chemistry (Weinheim An Der Bergstrasse, Germany)
Pan L, Aller SG. (2018) Allosteric Role of Substrate Occupancy Toward the Alignment of P-glycoprotein Nucleotide Binding Domains. Scientific Reports. 8: 14643
Radka CD, Radford LL, Massicano AVF, et al. (2018) Essential Metal Uptake in Gram-negative Bacteria: X-ray Fluorescence, Radioisotopes, and Cell Fractionation. Journal of Visualized Experiments : Jove
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