Adam Frost, Ph.D.

Affiliations: 
2008 Yale University, New Haven, CT 
Area:
Biochemistry
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"Adam Frost"
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Parents

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Vinzenz M. Unger grad student 2008 Yale
 (Structural basis of bilayer deformation by membrane -associated scaffolds.)

Collaborators

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Fabian Morales-Polanco collaborator (Neurotree)
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Publications

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von der Malsburg A, Sapp GM, Zuccaro KE, et al. (2023) Structural mechanism of mitochondrial membrane remodelling by human OPA1. Nature. 620: 1101-1108
Moss FR, Lincoff J, Tucker M, et al. (2023) Brominated lipid probes expose structural asymmetries in constricted membranes. Nature Structural & Molecular Biology
Manicki M, Aydin H, Abriata LA, et al. (2022) Structure and functionality of a multimeric human COQ7:COQ9 complex. Molecular Cell
Boone M, Wang L, Lawrence R, et al. (2022) A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation. Elife. 11
Schoof M, Wang L, Cogan JZ, et al. (2021) Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B. Nature Communications. 12: 7103
Gupta M, Azumaya CM, Moritz M, et al. (2021) CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. Biorxiv : the Preprint Server For Biology
Nguyen HC, Melo AA, Kruk J, et al. (2021) Photocatalytic LPOR forms helical lattices that shape membranes for chlorophyll synthesis. Nature Plants. 7: 437-444
Schoof M, Boone M, Wang L, et al. (2021) eIF2B conformation and assembly state regulates the integrated stress response. Elife. 10
Miller-Vedam LE, Bräuning B, Popova KD, et al. (2020) Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. Elife. 9
Gordon DE, Hiatt J, Bouhaddou M, et al. (2020) Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science (New York, N.Y.)
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