Bishuang Cai, Ph.D.

Affiliations: 
2013 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Cell Biology, Biochemistry
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Steve Caplan grad student 2013 University of Nebraska Medical Center
 (C-terminal Eps 15 homology domain (EHD) protein-mediated membrane vesiculation and control of glycosylphosphatidylinositol (GPI)-anchored protein trafficking.)
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Publications

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Wang X, Cai B, Yang X, et al. (2020) Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis. Cell Metabolism
Zheng Z, Nayak L, Wang W, et al. (2018) An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. Blood
Cai B, Kasikara C, Doran AC, et al. (2018) MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity. Science Signaling. 11
Kasikara C, Doran AC, Cai B, et al. (2018) The role of non-resolving inflammation in atherosclerosis. The Journal of Clinical Investigation. 128: 2713-2723
Yurdagul A, Doran AC, Cai B, et al. (2017) Mechanisms and Consequences of Defective Efferocytosis in Atherosclerosis. Frontiers in Cardiovascular Medicine. 4: 86
Doran AC, Ozcan L, Cai B, et al. (2017) CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. The Journal of Clinical Investigation
Cai B, Thorp EB, Doran AC, et al. (2017) MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis. The Journal of Clinical Investigation
Cai B, Thorp EB, Doran AC, et al. (2016) MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation. Proceedings of the National Academy of Sciences of the United States of America
Cai B, Xie S, Caplan S, et al. (2014) GRAF1 forms a complex with MICAL-L1 and EHD1 to cooperate in tubular recycling endosome vesiculation. Frontiers in Cell and Developmental Biology. 2: 22
Cai B, Xie S, Liu F, et al. (2014) Rapid degradation of the complement regulator, CD59, by a novel inhibitor. The Journal of Biological Chemistry. 289: 12109-25
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