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Ruiyu Xie, Ph.D.

Affiliations: 
2009 Pharmacology & Toxicology University of Arizona, Tucson, AZ 
Area:
Toxicology, Pharmacology
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"Ruiyu Xie"
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Terrence J. Monks grad student 2009 University of Arizona
 (Reactive oxygen species-induced necrotic cell death.)

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Li J, Wu X, Ke J, et al. (2022) TET1 dioxygenase is required for FOXA2-associated chromatin remodeling in pancreatic beta-cell differentiation. Nature Communications. 13: 3907
Ye J, Huang A, Wang H, et al. (2020) PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response. Cell Death & Disease. 11: 187
Wu X, Li G, Xie R. (2018) Decoding the role of TET family dioxygenases in lineage specification. Epigenetics & Chromatin. 11: 58
Li J, Wu X, Zhou Y, et al. (2018) Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC. Nucleic Acids Research
Shih HP, Seymour PA, Patel NA, et al. (2015) A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Reports
Wang A, Yue F, Li Y, et al. (2015) Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates. Cell Stem Cell. 16: 386-99
Xie R, Carrano AC, Sander M. (2015) A systems view of epigenetic networks regulating pancreas development and β-cell function. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 7: 1-11
Zhang F, Xie R, Munoz FM, et al. (2014) PARP-1 hyperactivation and reciprocal elevations in intracellular Ca2+ during ROS-induced nonapoptotic cell death. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 118-34
Xie R, Everett LJ, Lim HW, et al. (2013) Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells. Cell Stem Cell. 12: 224-37
van der Meulen T, Xie R, Kelly OG, et al. (2012) Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells. Plos One. 7: e52181
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