Kirsten E. Hoff, Ph.D.

Affiliations: 
2013 Biochemistry Duke University, Durham, NC 
Area:
Biochemistry
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Richard G. Brennan grad student 2013 Duke
 (Mapping RNA Binding Surfaces on Hfq Using Tryptophan Fluorescence Quenching.)
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Publications

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Wojtaszek JL, Hoff KE, Longley MJ, et al. (2023) Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA. Nucleic Acids Research
Orans J, Kovach AR, Hoff KE, et al. (2020) Crystal structure of an Escherichia coli Hfq Core (residues 2-69)-DNA complex reveals multifunctional nucleic acid binding sites. Nucleic Acids Research
Hoff KE, DeBalsi KL, Sanchez-Quintero MJ, et al. (2018) Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome. Plos One. 13: e0203198
DeBalsi KL, Longley MJ, Hoff KE, et al. (2017) Synergistic Effects of the in cis T251I and P587L Mitochondrial DNA Polymerase γ Disease Mutations. The Journal of Biological Chemistry
Varma H, Faust PL, Iglesias AD, et al. (2016) Whole exome sequencing identifies a homozygous POLG2 missense variant in an infant with fulminant hepatic failure and mitochondrial DNA depletion. European Journal of Medical Genetics
DeBalsi KL, Hoff KE, Copeland WC. (2016) Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases. Ageing Research Reviews
Kovach AR, Hoff KE, Canty JT, et al. (2014) Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes. Rna (New York, N.Y.). 20: 1548-59
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