Sabine Hellwig, Ph.D.

Affiliations: 
2007 University of Utah, Salt Lake City, UT 
Area:
Molecular Biology
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"Sabine Hellwig"
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Brenda L. Bass grad student 2007 University of Utah
 (The fate of edited RNA in Caenorhabditis elegans.)
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Publications

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Weir MC, Shu ST, Patel RK, et al. (2018) Selective inhibition of the myeloid Src-family kinase Fgr potently suppresses AML cell growth in vitro and in vivo. Acs Chemical Biology
Weir MC, Hellwig S, Tan L, et al. (2017) Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth. Plos One. 12: e0181178
Weir MC, Shu S, Hellwig S, et al. (2017) A Unique N-Phenylbenzamide Inhibitor Targeting Non-Receptor Tyrosine Kinases Potently Suppresses AML Cell Growth In Vitro and In Vivo Blood. 130: 3813-3813
Weir M, Hellwig S, Gray NS, et al. (2015) Abstract A25: Dual inhibition of Flt3 and Fes tyrosine kinases potently blocks proliferation of AML cells expressing an active Flt3 mutant. Clinical Cancer Research. 21
Weir MC, Hellwig S, Patel R, et al. (2015) Abstract B180: Multi-targeted tyrosine kinase inhibitors potently suppress FLT3-ITD+ AML cell growth Molecular Cancer Therapeutics. 14
Weir M, Hellwig S, Gray NS, et al. (2013) Abstract 2086: Dual inhibitors of Flt3 and c-Fest tyrosine kinases potently inhibit proliferation of AML cells expressing an active Flt3 mutant. Cancer Research. 73: 2086-2086
Hellwig S, Miduturu CV, Kanda S, et al. (2012) Small-molecule inhibitors of the c-Fes protein-tyrosine kinase. Chemistry & Biology. 19: 529-40
Hellwig S, Smithgall TE. (2011) Structure and regulation of the c-Fes protein-tyrosine kinase. Frontiers in Bioscience (Landmark Edition). 16: 3146-55
Hellwig S, Gray NS, Smithgall TE. (2011) Abstract A234: Identification and characterization of inhibitor-resistant mutants of the protein-tyrosine kinase c-Fes. Molecular Cancer Therapeutics. 10
Aruscavage PJ, Hellwig S, Bass BL. (2010) Small DNA pieces in C. elegans are intermediates of DNA fragmentation during apoptosis. Plos One. 5: e11217
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