Sunil K. Upadhyay, Ph.D.
Affiliations: | 2011 | University of New Orleans, New Orleans, LA, United States |
Area:
Organic ChemistryGoogle:
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Parents
Sign in to add mentor| Branko S. Jursic | grad student | 2011 | University of New Orleans | |
| (Synthesis and Antifungal Evaluation of Spirostane Saponins.) | ||||
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Publications
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| Alyamani M, Emamekhoo H, Park S, et al. (2018) HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer. The Journal of Clinical Investigation |
| Emamekhoo H, Alyamani M, Park S, et al. (2018) HSD3B1 genotype and abiraterone (Abi) metabolites in patients (pts) with prostate cancer (PCa). Journal of Clinical Oncology. 36: 325-325 |
| Alyamani M, Li Z, Berk M, et al. (2017) Steroidogenic Metabolism of Galeterone Reveals a Diversity of Biochemical Activities. Cell Chemical Biology |
| Li Z, Alyamani M, Li J, et al. (2016) Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy. Nature. 533: 547-51 |
| Li Z, Bishop AC, Alyamani M, et al. (2015) Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer. Nature. 523: 347-51 |
| Garrido M, Peng HM, Yoshimoto FK, et al. (2014) A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone. The Journal of Steroid Biochemistry and Molecular Biology. 143: 1-10 |
| He S, Senter TJ, Pollock J, et al. (2014) High-affinity small-molecule inhibitors of the menin-mixed lineage leukemia (MLL) interaction closely mimic a natural protein-protein interaction. Journal of Medicinal Chemistry. 57: 1543-56 |
| Grembecka JE, He S, Senter TJ, et al. (2014) Abstract 2534: High-affinity small molecule inhibitors of the menin-MLL interaction reverse oncogenic transformation mediated by MLL fusion proteins in leukemia Cancer Research. 74: 2534-2534 |
| Cammarata A, Upadhyay SK, Jursic BS, et al. (2011) Antifungal activity of 2α,3β-functionalized steroids stereoselectively increases with the addition of oligosaccharides. Bioorganic & Medicinal Chemistry Letters. 21: 7379-86 |
| Upadhyay SK, Creech CC, Bowdy KL, et al. (2011) Synthesis and antifungal activity of functionalized 2,3-spirostane isomers. Bioorganic & Medicinal Chemistry Letters. 21: 2826-31 |