Christopher T. Veldkamp, Ph.D.

Affiliations: 
2006 Medical College of Wisconsin, Milwaukee, WI, United States 
Area:
Biochemistry, Molecular Biology
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Brian F. Volkman grad student 2006 Medical College of Wisconsin
 (Structural studies of the stromal cell-derived factor-1/CXCL12 monomer -dimer equilibrium by multidimensional NMR and fluorescence spectroscopy.)
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Publications

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Witt RN, Nickel KS, Binns JR, et al. (2023) NMR indicates the N-termini of PSGL1 and CCR7 bind competitively to the chemokine CCL21. Biochemistry and Biophysics Reports. 35: 101524
Brandum EP, Jørgensen AS, Calvo MB, et al. (2022) Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic Tails. International Journal of Molecular Sciences. 23
Lewandowski EM, Kroeck KG, Jacobs LMC, et al. (2022) Structural Insights into Molecular Recognition by Human Chemokine CCL19. Biochemistry
Jørgensen AS, Brandum EP, Mikkelsen JM, et al. (2021) The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus. Cellular and Molecular Life Sciences : Cmls
Gutjahr JC, Crawford KS, Jensen DR, et al. (2021) The dimeric form of CXCL12 binds to atypical chemokine receptor 1. Science Signaling. 14
Jørgensen AS, Larsen O, Uetz-von Allmen E, et al. (2019) Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7. Frontiers in Immunology. 10: 2156
Jørgensen AS, Adogamhe PE, Laufer JM, et al. (2018) CCL19 with CCL21-tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells. Journal of Leukocyte Biology
Moussouras NA, Getschman AE, Lackner ER, et al. (2017) Differences in Sulfotyrosine Binding amongst CXCR1 and CXCR2 Chemokine Ligands. International Journal of Molecular Sciences. 18
Phillips AJ, Taleski D, Koplinski CA, et al. (2017) CCR7 Sulfotyrosine Enhances CCL21 Binding. International Journal of Molecular Sciences. 18
Ziarek JJ, Kleist AB, London N, et al. (2017) Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation. Science Signaling. 10
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