Karine Auclair

Affiliations: 
2002- Chemistry McGill University, Montreal, QC, Canada 
Area:
Organic Chemistry, Biochemistry
Website:
https://www.mcgill.ca/chemistry/faculty/auclair
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"Karine Auclair"
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Parents

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John C. Vederas grad student 1999 University of Alberta
 (Biosynthetic studies on the polyketide lovastatin : enzyme-catalyzed Diels-Alder reactions.)
Paul R. Ortiz de Montellano post-doc 2002 UCSF

Children

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Aaron T. Larsen grad student 2012 McGill
Kenward Vong grad student 2013 McGill
Dustin Duncan grad student 2016-2021 McGill
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Publications

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Van Oers TJ, Piercey A, Belovodskiy A, et al. (2023) Deuteration for Metabolic Stabilization of SARS-CoV-2 Inhibitors GC373 and Nirmatrelvir. Organic Letters. 25: 5885-5889
Kaabel S, Therien JPD, Deschênes CE, et al. (2021) Enzymatic depolymerization of highly crystalline polyethylene terephthalate enabled in moist-solid reaction mixtures. Proceedings of the National Academy of Sciences of the United States of America. 118
Duncan D, Lupien A, Behr MA, et al. (2021) Effect of pH on the antimicrobial activity of the macrophage metabolite itaconate. Microbiology (Reading, England). 167
Guan J, Spry C, Tjhin ET, et al. (2021) Exploring Heteroaromatic Rings as a Replacement for the Labile Amide of Antiplasmodial Pantothenamides. Journal of Medicinal Chemistry
Swain A, Bambouskova M, Kim H, et al. (2020) Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages. Nature Metabolism. 2: 594-602
Hammerer F, Ostadjoo S, Dietrich K, et al. (2020) Rapid mechanoenzymatic saccharification of lignocellulosic biomass without bulk water or chemical pre-treatment Green Chemistry. 22: 3877-3884
Kaabel S, Friščić T, Auclair K. (2020) Cover Feature: Mechanoenzymatic Transformations in the Absence of Bulk Water: A More Natural Way of Using Enzymes (ChemBioChem 6/2020) Chembiochem. 21: 740-740
Ostadjoo S, Hammerer F, Dietrich K, et al. (2019) Efficient Enzymatic Hydrolysis of Biomass Hemicellulose in the Absence of Bulk Water. Molecules (Basel, Switzerland). 24
Kaabel S, Friscic T, Auclair K. (2019) Mechanoenzymatic transformations in the absence of bulk water - a more natural way of using enzymes. Chembiochem : a European Journal of Chemical Biology
Hammerer F, Ostadjoo S, Friscic T, et al. (2019) Towards controlling the reactivity of enzymes in mechanochemistry: inert surfaces protect β-glucosidase activity during ball milling. Chemsuschem
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