Prashant Rajbhandari, Ph.D.

Affiliations: 
2013 Molecular and Cellular Pharmacology University of Wisconsin, Madison, Madison, WI 
Area:
Oncology, Biochemistry
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"Prashant Rajbhandari"
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Parents

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Elaine T. Alarid grad student 2013 UW Madison
 (Phosphorylation-dependent prolyl cis/trans isomerase pin1 regulation of estrogen receptor-alpha functions in breast cancer.)
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Publications

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Zhou Z, Moore TM, Drew BG, et al. (2020) Estrogen receptor α controls metabolism in white and brown adipocytes by regulating and mitochondrial remodeling. Science Translational Medicine. 12
Rajbhandari P, Arneson D, Hart SK, et al. (2019) Author response: Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes Elife
Sallam T, Jones M, Thomas BJ, et al. (2018) Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. Nature Medicine
Zhou Z, Ribas V, Rajbhandari P, et al. (2018) Estrogen receptor alpha protects pancreatic beta cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress. The Journal of Biological Chemistry
Zhang L, Rajbhandari P, Priest C, et al. (2017) Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP. Elife. 6
Wang J, Rajbhandari P, Damianov A, et al. (2017) RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. The Journal of Clinical Investigation
Rajbhandari P, Ozers MS, Solodin NM, et al. (2015) Peptidylprolyl Isomerase Pin1 Directly Enhances the DNA Binding Functions of Estrogen Receptor α. The Journal of Biological Chemistry. 290: 13749-62
Tian D, Solodin NM, Rajbhandari P, et al. (2015) A kinetic model identifies phosphorylated estrogen receptor-α (ERα) as a critical regulator of ERα dynamics in breast cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2022-31
Rajbhandari P, Schalper KA, Solodin NM, et al. (2014) Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation. Oncogene. 33: 1438-47
Powers GL, Rajbhandari P, Solodin NM, et al. (2013) The proteasome inhibitor bortezomib induces an inhibitory chromatin environment at a distal enhancer of the estrogen receptor-α gene. Plos One. 8: e81110
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