Sepehr Ehsani, Ph.D.

Affiliations: 
2012 Laboratory Medicine and Pathobiology University of Toronto, Toronto, ON, Canada 
Area:
Genetics, Cell Biology, Neuroscience Biology, Bioinformatics Biology, Biochemistry
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"Sepehr Ehsani"
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Parents

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Gerold Schmitt-Ulms grad student 2012 University of Toronto
 (The Significance of the Evolutionary Relationship of Prion Proteins and ZIP Transporters in Health and Disease.)
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Publications

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Schmitt-Ulms G, Mehrabian M, Williams D, et al. (2021) The IDIP framework for assessing protein function and its application to the prion protein. Biological Reviews of the Cambridge Philosophical Society
Khurana V, Peng J, Chung CY, et al. (2017) Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Systems
Brethour D, Mehrabian M, Williams D, et al. (2017) A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition. Scientific Reports. 7: 40313
Mehrabian M, Ehsani S, Schmitt-Ulms G. (2014) An emerging role of the cellular prion protein as a modulator of a morphogenetic program underlying epithelial-to-mesenchymal transition. Frontiers in Cell and Developmental Biology. 2: 53
Narayan P, Ehsani S, Lindquist S. (2014) Combating neurodegenerative disease with chemical probes and model systems. Nature Chemical Biology. 10: 911-20
Pocanschi CL, Ehsani S, Mehrabian M, et al. (2013) The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer. Plos One. 8: e72446
Ehsani S, Salehzadeh A, Huo H, et al. (2012) LIV-1 ZIP ectodomain shedding in prion-infected mice resembles cellular response to transition metal starvation. Journal of Molecular Biology. 422: 556-74
Ehsani S, Mehrabian M, Pocanschi CL, et al. (2012) The ZIP-prion connection. Prion. 6: 317-21
Harbi D, Parthiban M, Gendoo DM, et al. (2012) PrionHome: a database of prions and other sequences relevant to prion phenomena. Plos One. 7: e31785
Ehsani S, Tao R, Pocanschi CL, et al. (2011) Evidence for retrogene origins of the prion gene family. Plos One. 6: e26800
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