Timothy D. Calamaras, Ph.D.
Affiliations: | 2014 | Molecular Medicine | Boston University, Boston, MA, United States |
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BiochemistryGoogle:
"Timothy Calamaras"Mean distance: (not calculated yet)
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Sign in to add mentorWilson S. Colucci | grad student | 2014 | Boston University | |
(Role of oxidative modifications of LKB1 in promoting myocardial hypertrophy.) |
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Publications
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Calamaras TD, Pande S, Baumgartner RA, et al. (2021) Mixed Lineage Kinase 3 mediates PKG1α impact on cardiac function and controls blood pressure through separate mechanisms. Jci Insight |
Calamaras TD, Baumgartner RA, Aronovitz MJ, et al. (2018) Mixed Lineage Kinase 3 (MLK3) Prevents Cardiac Dysfunction and Structural Remodeling with Pressure Overload. American Journal of Physiology. Heart and Circulatory Physiology |
Sverdlov AL, Elezaby A, Qin F, et al. (2016) Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. Journal of the American Heart Association. 5 |
Miller EJ, Calamaras T, Elezaby A, et al. (2015) Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. Journal of the American Heart Association. 5 |
Thoonen R, Giovanni S, Govindan S, et al. (2015) A Molecular Screen Identifies Cardiac Myosin Binding Protein-C as a Protein Kinase G I Alpha Substrate. Circulation. Heart Failure |
Calamaras TD, Lee C, Lan F, et al. (2015) The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling. Free Radical Biology & Medicine. 82: 137-46 |
Calamaras TD, Lee C, Lan F, et al. (2012) Post-translational modification of serine/threonine kinase LKB1 via Adduction of the Reactive Lipid Species 4-Hydroxy-trans-2-nonenal (HNE) at lysine residue 97 directly inhibits kinase activity. The Journal of Biological Chemistry. 287: 42400-6 |
Kumar V, Calamaras TD, Haeussler D, et al. (2012) Cardiovascular redox and ox stress proteomics. Antioxidants & Redox Signaling. 17: 1528-59 |
Qin F, Siwik DA, Luptak I, et al. (2012) The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation. 125: 1757-64, S1-6 |
Calamaras TD, Lee C, Siwik DA, et al. (2012) The Lipid Peroxidation Product 4-Hydroxy-2-Nonenal (HNE) Causes Cardiac Myocyte Hypertrophy and Activates Hypertrophic MAP Kinase Signaling Free Radical Biology and Medicine. 53: S156 |