Zhengxiang Zhu, Ph.D.

Affiliations: 
2006 University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmaceutical Chemistry
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"Zhengxiang Zhu"
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John K. Buolamwini grad student 2006 UTHSC
 (Studies on novel tetrahydroisoquinoline analogues of the ENT1 nucleoside transporter inhibitor, S6-(4-nitrobenzyl) mercaptopurine riboside (NBMPR).)
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Publications

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Zhu Z, Buolamwini JK. (2008) Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorganic & Medicinal Chemistry. 16: 3848-65
Zhu Z, Hofmann PA, Buolamwini JK. (2007) Cardioprotective effects of novel tetrahydroisoquinoline analogs of nitrobenzylmercaptopurine riboside in an isolated perfused rat heart model of acute myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2921-6
Zhu Z, Furr J, Buolamwini JK. (2003) Synthesis and flow cytometric evaluation of novel 1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of nitrobenzylmercaptopurine riboside (NBMPR) designed for probing its conformation when bound to the es nucleoside transporter. Journal of Medicinal Chemistry. 46: 831-7
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