Jamie E. Jennings-Gee, Ph.D.
Affiliations: | 2002 | Wake Forest University School of Medicine, Winston-Salem, NC, United States |
Area:
Biochemistry, Molecular BiologyGoogle:
"Jamie Jennings-Gee"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Suzy V. Torti | grad student | 2002 | Wake Forest School of Medicine | |
| (Differential regulation of ferritin H by TNF -alpha in normal and transformed cells.) | ||||
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Publications
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| Gmeiner WH, Jennings-Gee J, Stuart CH, et al. (2015) Thymineless death in F10-treated AML cells occurs via lipid raft depletion and Fas/FasL co-localization in the plasma membrane with activation of the extrinsic apoptotic pathway Leukemia Research. 39: 229-235 |
| Gmeiner WH, Boyacioglu O, Stuart CH, et al. (2015) The cytotoxic and pro-apoptotic activities of the novel fluoropyrimidine F10 Towards prostate cancer cells are enhanced by Zn2+-chelation and inhibiting the serine protease Omi/HtrA2 Prostate. 75: 360-369 |
| Pardee TS, Stadelman K, Jennings-Gee J, et al. (2014) The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells. Oncotarget. 5: 4170-9 |
| Gmeiner WH, Lema-Tome C, Gibo D, et al. (2014) Selective anti-tumor activity of the novel fluoropyrimidine polymer F10 towards G48a orthotopic GBM tumors. Journal of Neuro-Oncology. 116: 447-54 |
| Jennings-Gee J, Pardee TS, Gmeiner WH. (2013) Replication-dependent irreversible topoisomerase 1 poisoning is responsible for FdUMP[10] anti-leukemic activity. Experimental Hematology. 41: 180-188.e4 |
| Pardee T, Jennings-Gee J, Stadelman K, et al. (2013) The Poison Oligonucleotide F10 Is Efficiently Taken Up By, and Highly Effective Against, Acute Lymphoblastic Leukemia While Sparing Normal Hematopoietic Cells Blood. 122: 2674-2674 |
| Pardee TS, Gomes E, Jennings-Gee J, et al. (2012) Unique dual targeting of thymidylate synthase and topoisomerase1 by FdUMP[10] results in high efficacy against AML and low toxicity. Blood. 119: 3561-70 |
| Pardee T, Jennings-Gee J, Alexander P, et al. (2012) Thymidylate Synthase Inhibition with the Novel Fluoropyrimidine FdUMP[10] Is Highly Effective Against Acute Lymphoblastic Leukemia Blood. 120: 1505-1505 |
| Pardee T, Gomes E, Jennings-Gee J, et al. (2010) The Novel Fluoropyrimidine FdUMP[10] Is Highly Active Against Acute Myeloid Leukemia Blood. 116: 3302-3302 |
| Gomes E, Jennings-Gee J, Gmeiner WH. (2010) Abstract 1637: The MEK/Erk pathway is required for PC3 cell survival following FdUMP[10] treatment Cancer Research. 70: 1637-1637 |