Daniel A. Mordes, Ph.D.

Affiliations: 
2008 Vanderbilt University, Nashville, TN 
Area:
Biochemistry, Molecular Biology, Cell Biology
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"Daniel Mordes"
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David K. Cortez grad student 2008 Vanderbilt
 (Activation of the DNA damage response kinase ATR.)
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Publications

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Farhan SMK, Howrigan DP, Abbott LE, et al. (2019) Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein. Nature Neuroscience
Mordes DA, Prudencio M, Goodman LD, et al. (2018) Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients. Acta Neuropathologica Communications. 6: 55
Zhang Y, Burberry A, Wang JY, et al. (2018) The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis. Genes & Development
Hill SJ, Mordes DA, Cameron LA, et al. (2016) Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage. Proceedings of the National Academy of Sciences of the United States of America
Mordes DA, Cortez D. (2009) Signaling at stalled replication forks The Dna Damage Response: Implications On Cancer Formation and Treatment. 25-45
Mordes DA, Nam EA, Cortez D. (2008) Dpb11 activates the Mec1-Ddc2 complex. Proceedings of the National Academy of Sciences of the United States of America. 105: 18730-4
Xu X, Vaithiyalingam S, Glick GG, et al. (2008) The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling. Molecular and Cellular Biology. 28: 7345-53
Mordes DA, Cortez D. (2008) Activation of ATR and related PIKKs. Cell Cycle (Georgetown, Tex.). 7: 2809-12
Mordes DA, Glick GG, Zhao R, et al. (2008) TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes & Development. 22: 1478-89
Ball HL, Ehrhardt MR, Mordes DA, et al. (2007) Function of a conserved checkpoint recruitment domain in ATRIP proteins. Molecular and Cellular Biology. 27: 3367-77
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