Kjerstin M. Owens, Ph.D.

Affiliations: 
2008 University of Iowa, Iowa City, IA 
Area:
Cell Biology, Molecular Biology
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"Kjerstin Owens"
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Douglas R. Spitz grad student 2008 University of Iowa
 (Expression of a mutant succinate dehydrogenase subunit D and its role in superoxide production and genomic instability.)
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Publications

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Bajpai P, Singh B, Owens KM, et al. (2017) Abstract 1494: Interethnic germline variants in mitochondrial DNA polymerase (POLG1) induce mitochondrial dysfunction and confer tumorigenic properties Cancer Research. 77: 1494-1494
Singh B, Kulawiec M, Owens KM, et al. (2016) Sustained Early Disruption of Mitochondrial Function Contributes to Arsenic-Induced Prostate Tumorigenesis. Biochemistry. Biokhimiia. 81: 1089-1100
Singh B, Owens KM, Bajpai P, et al. (2015) Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties. Plos One. 10: e0139846
Singh B, Li X, Owens KM, et al. (2015) Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome. Plos One. 10: e0140409
Owens KM, Aykin-Burns N, Dayal D, et al. (2012) Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2(-•) and H2O2. Free Radical Biology & Medicine. 52: 160-6
Ayyasamy V, Owens KM, Desouki MM, et al. (2011) Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin. Plos One. 6: e24792
Hall BM, Owens KM, Singh KK. (2011) Distinct functions of evolutionary conserved MSF1 and late embryogenesis abundant (LEA)-like domains in mitochondria. The Journal of Biological Chemistry. 286: 39141-52
Owens KM, Kulawiec M, Desouki MM, et al. (2011) Impaired OXPHOS complex III in breast cancer. Plos One. 6: e23846
Aykin-Burns N, Slane BG, Liu AT, et al. (2011) Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species. Radiation Research. 175: 150-8
Owens⁎ KM, Ayyasamy V, Koul MS, et al. (2011) Contribution of polymerase gamma mutations to the Warburg effect and its role in cancer Mitochondrion. 11: 658
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