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Chih-Ling Chou, Ph.D.

Affiliations: 
2003 Johns Hopkins University, Baltimore, MD 
Area:
Medical Biophysics, Immunology, Molecular Biology
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"Chih-Ling Chou"
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Scheherazade Sadegh-Nasseri grad student 2003 Johns Hopkins
 (Defining the mechanism of MHC class II peptide editing by HLA-DM: I. HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. II. Mapping the interaction surface of DR1 with DM by superantigen blocking. III. Determinatio)

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Publications

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Sadegh-Nasseri S, Chou CL, Hartman IZ, et al. (2012) How HLA-DM works: recognition of MHC II conformational heterogeneity. Frontiers in Bioscience (Scholar Edition). 4: 1325-32
Sadegh-Nasseri S, Natarajan S, Chou CL, et al. (2010) Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection. Immunologic Research. 47: 56-64
Narayan K, Su KW, Chou CL, et al. (2009) HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1. Molecular Immunology. 46: 3157-62
Chou CL, Mirshahidi S, Su KW, et al. (2008) Short peptide sequences mimic HLA-DM functions. Molecular Immunology. 45: 1935-43
Narayan K, Chou CL, Kim A, et al. (2007) HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes. Nature Immunology. 8: 92-100
Fang M, Tao YX, He F, et al. (2003) Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics. The Journal of Biological Chemistry. 278: 36669-75
Chou CL, Sadegh-Nasseri S. (2000) HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. The Journal of Experimental Medicine. 192: 1697-706
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