Emily J. Westover, Ph.D.

Affiliations: 
2003 Washington University, Saint Louis, St. Louis, MO 
Area:
Organic Chemistry, Biochemistry, Cell Biology
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"Emily Westover"
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Parents

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Douglas F. Covey grad student 2003 Washington University
 (The unnatural enantiomer of cholesterol: Chemical synthesis and biological studies.)
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Publications

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Minogue S, Chu KM, Westover EJ, et al. (2010) Relationship between phosphatidylinositol 4-phosphate synthesis, membrane organization, and lateral diffusion of PI4KIIalpha at the trans-Golgi network. Journal of Lipid Research. 51: 2314-24
Gale SE, Westover EJ, Dudley N, et al. (2009) Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions. The Journal of Biological Chemistry. 284: 1755-64
Westover EJ, Lin X, Riehl TE, et al. (2006) Rapid transient absorption and biliary secretion of enantiomeric cholesterol in hamsters. Journal of Lipid Research. 47: 2374-81
Yang C, McDonald JG, Patel A, et al. (2006) Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. The Journal of Biological Chemistry. 281: 27816-26
Westover EJ, Covey DF. (2006) Synthesis of ent-25-hydroxycholesterol. Steroids. 71: 484-8
Liu J, Chang CC, Westover EJ, et al. (2005) Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies. The Biochemical Journal. 391: 389-97
Westover EJ, Covey DF. (2004) The enantiomer of cholesterol. The Journal of Membrane Biology. 202: 61-72
Li Y, Ge M, Ciani L, et al. (2004) Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages. The Journal of Biological Chemistry. 279: 37030-9
Zitzer A, Westover EJ, Covey DF, et al. (2003) Differential interaction of the two cholesterol-dependent, membrane-damaging toxins, streptolysin O and Vibrio cholerae cytolysin, with enantiomeric cholesterol. Febs Letters. 553: 229-31
Westover EJ, Covey DF, Brockman HL, et al. (2003) Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers. The Journal of Biological Chemistry. 278: 51125-33
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