Padmalatha Channavajhala, Ph.D.

Affiliations: 
2001 Boston University, Boston, MA, United States 
Area:
Immunology, Oncology
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"Padmalatha Channavajhala"
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David C. Seldin grad student 2001 Boston University
 (Dysregulated signaling pathways in T cell lymphomas derived from CK2 transgenic mice.)
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Publications

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Channavajhala PL, Rao VR, Spaulding V, et al. (2005) hKSR-2 inhibits MEKK3-activated MAP kinase and NF-kappaB pathways in inflammation. Biochemical and Biophysical Research Communications. 334: 1214-8
Luciano BS, Hsu S, Channavajhala PL, et al. (2004) Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity. The Journal of Biological Chemistry. 279: 52117-23
Channavajhala PL, Wu L, Cuozzo JW, et al. (2003) Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signaling. The Journal of Biological Chemistry. 278: 47089-97
Channavajhala P, Seldin DC. (2002) Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis. Oncogene. 21: 5280-8
Shen J, Channavajhala P, Seldin DC, et al. (2001) Phosphorylation by the protein kinase CK2 promotes calpain-mediated degradation of IkappaBalpha. Journal of Immunology (Baltimore, Md. : 1950). 167: 4919-25
Xu X, Landesman-Bollag E, Channavajhala PL, et al. (1999) Murine protein kinase CK2: gene and oncogene. Molecular and Cellular Biochemistry. 191: 65-74
Rifkin IR, Channavajhala PL, Kiefer HL, et al. (1998) Acceleration of lpr lymphoproliferative and autoimmune disease by transgenic protein kinase CK2 alpha. Journal of Immunology (Baltimore, Md. : 1950). 161: 5164-70
Landesman-Bollag E, Channavajhala PL, Cardiff RD, et al. (1998) p53 deficiency and misexpression of protein kinase CK2alpha collaborate in the development of thymic lymphomas in mice. Oncogene. 16: 2965-74
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