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Nodar Makharashvili, Ph.D.

Affiliations: 
2009 Saint Louis University, St. Louis, MO, United States 
Area:
Biochemistry, Genetics
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"Nodar Makharashvili"
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Sergey Korolev grad student 2009 Saint Louis University
 (What RecFOR are for: Structure-function studies of recombination mediator proteins.)

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Publications

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Deshpande RA, Myler LR, Soniat MM, et al. (2020) DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP. Science Advances. 6: eaay0922
Makharashvili N, Arora S, Yin Y, et al. (2018) Sae2/CtIP prevents R-loop accumulation in eukaryotic cells. Elife. 7
Leung JW, Makharashvili N, Agarwal P, et al. (2017) ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair. Genes & Development
Makharashvili N, Paull TT. (2015) CtIP: A DNA damage response protein at the intersection of DNA metabolism. Dna Repair. 32: 75-81
Barton O, Naumann SC, Diemer-Biehs R, et al. (2014) Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1. The Journal of Cell Biology. 206: 877-94
Makharashvili N, Tubbs AT, Yang SH, et al. (2014) Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection. Molecular Cell. 54: 1022-33
Fu Q, Chow J, Bernstein KA, et al. (2014) Phosphorylation-regulated transitions in an oligomeric state control the activity of the Sae2 DNA repair enzyme. Molecular and Cellular Biology. 34: 778-93
Fu Q, Chow J, Bernstein KA, et al. (2014) Correction to Phosphorylation-regulated transitions in an oligomeric state control the activity of the Sae2 DNA repair enzyme [Molecular and Cellular Biology, 34, 5, (2014), 778-793] Molecular and Cellular Biology. 34: 4213-4213
Makharashvili N, Mi T, Koroleva O, et al. (2009) RecR-mediated modulation of RecF dimer specificity for single- and double-stranded DNA. The Journal of Biological Chemistry. 284: 1425-34
Koroleva O, Makharashvili N, Courcelle CT, et al. (2007) Structural conservation of RecF and Rad50: implications for DNA recognition and RecF function. The Embo Journal. 26: 867-77
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