Anders Skov Kristensen, Ph.D.
Affiliations: | Medicinal Chemistry | University of Copenhagen, København, Denmark |
Area:
Glutamate receptors, SLC6 transportersGoogle:
"Anders Skov Kristensen"Mean distance: 10.19 | S | N | B | C | P |
Parents
Sign in to add mentor| Stephen F. Traynelis | post-doc | 2004-2006 | Emory University School of Medicine (Neurotree) |
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Publications
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| Bay Y, Egeberg Jeppesen M, Frydenvang K, et al. (2024) The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2. Febs Letters |
| Bay Y, Venskutonytė R, Frantsen SM, et al. (2023) Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. The Febs Journal |
| Francotte P, Bay Y, Goffin E, et al. (2023) Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators. European Journal of Medicinal Chemistry. 264: 116036 |
| Chałupnik P, Vialko A, Pickering DS, et al. (2022) Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype. International Journal of Molecular Sciences. 23 |
| Ismail V, Zachariassen LG, Godwin A, et al. (2022) Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome. American Journal of Human Genetics |
| Perszyk RE, Kristensen AS, Lyuboslavsky P, et al. (2021) Three-dimensional missense tolerance ratio analysis. Genome Research |
| Stenum-Berg C, Musgaard M, Chavez-Abiega S, et al. (2019) Mutational analysis and modeling of negative allosteric modulator binding sites in AMPA receptors. Molecular Pharmacology |
| Munro L, Ladefoged LK, Padmanathan V, et al. (2019) Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage Clamp Fluorometry. Molecular Pharmacology |
| Kate Ladefoged L, Munro L, Kristensen AS, et al. (2019) Molecular Insight into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-HT3A Receptors Biophysical Journal. 116: 479a |
| Ladefoged LK, Munro L, Pedersen AJ, et al. (2018) Modeling and mutational analysis of the binding mode for the multimodal antidepressant drug vortioxetine to the human 5-HT3A receptor. Molecular Pharmacology |