W J. Pledger

Affiliations: 
University of South Florida, Tampa, FL, United States 
Area:
Biochemistry, Cell Biology
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"W Pledger"
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Publications

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Sharma SS, Pledger WJ. (2016) The non-canonical functions of p27(Kip1) in normal and tumor biology. Cell Cycle (Georgetown, Tex.). 1-13
Sharma SS, Ma L, Pledger WJ. (2015) p27Kip1 inhibits the cell cycle through non-canonical G1/S phase-specific gatekeeper mechanism. Cell Cycle (Georgetown, Tex.). 14: 3954-64
Bagui TK, Sharma SS, Ma L, et al. (2013) Proliferative status regulates HDAC11 mRNA abundance in nontransformed fibroblasts. Cell Cycle (Georgetown, Tex.). 12: 3433-41
Fu W, Sharma SS, Ma L, et al. (2013) Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor. Cell Death & Disease. 4: e566
Hodul PJ, Dong Y, Husain K, et al. (2013) Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. Plos One. 8: e52526
Sharma SS, Ma L, Bagui TK, et al. (2012) A p27Kip1 mutant that does not inhibit CDK activity promotes centrosome amplification and micronucleation. Oncogene. 31: 3989-98
Fu W, Ma L, Chu B, et al. (2011) The cyclin-dependent kinase inhibitor SCH 727965 (dinacliclib) induces the apoptosis of osteosarcoma cells. Molecular Cancer Therapeutics. 10: 1018-27
Kazi A, Carie A, Blaskovich MA, et al. (2009) Blockade of protein geranylgeranylation inhibits Cdk2-dependent p27Kip1 phosphorylation on Thr187 and accumulates p27Kip1 in the nucleus: implications for breast cancer therapy. Molecular and Cellular Biology. 29: 2254-63
Bagui TK, Cui D, Roy S, et al. (2009) Inhibition of p27Kip1 gene transcription by mitogens. Cell Cycle (Georgetown, Tex.). 8: 115-24
He L, Yang H, Ma Y, et al. (2008) Identification of Aurora-A as a direct target of E2F3 during G2/M cell cycle progression. The Journal of Biological Chemistry. 283: 31012-20
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