Christopher L. Brett, Ph.D. M.D.

Affiliations: 
Biology Concordia University (Canada), Montreal, QC, Canada 
Area:
Ion transport, pH regulation, endocytosis, membrane fusion, synaptic plasticity
Website:
http://www.brettlab.org/
Google:
"Christopher Brett Concordia Montreal"
Mean distance: 9.89 (cluster 56)
 
SNBCP
Cross-listing: Cell Biology Tree

Parents

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John Church grad student 1996-1999 UBC (Neurotree)
Mark Donowitz grad student 1999-2005 Johns Hopkins (Neurotree)
 (pHome, sodium /hydrogen exchange and vesicle trafficking.)
Rajini Rao grad student 1999-2005 Johns Hopkins (Neurotree)
 (pHome, sodium /hydrogen exchange and vesicle trafficking.)
Alexey J. Merz post-doc 2005-2010 UW Medical School

Children

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Adam J MacDonald grad student (Neurotree)
BETA: Related publications

Publications

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Golden CK, Kazmirchuk TDD, McNally EK, et al. (2022) A two-tiered system for selective receptor and transporter protein degradation. Plos Genetics. 18: e1010446
Mattie S, Kazmirchuk T, Mui J, et al. (2019) Visualization of SNARE-Mediated Organelle Membrane Hemifusion by Electron Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1860: 361-377
Karim MA, Samyn DR, Brett CL. (2019) A Cell-Free Content Mixing Assay for SNARE-Mediated Multivesicular Body-Vacuole Membrane Fusion. Methods in Molecular Biology (Clifton, N.J.). 1860: 289-301
McNally EK, Brett CL. (2018) The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation. Nature Communications. 9: 5358
Karim MA, McNally EK, Samyn DR, et al. (2018) Rab-Effector-Kinase Interplay Modulates Intralumenal Fragment Formation during Vacuole Fusion. Developmental Cell. 47: 80-97.e6
Karim MA, Brett CL. (2017) The Na+(K+)/H+ exchanger Nhx1 controls multivesicular body-vacuolar lysosome fusion. Molecular Biology of the Cell
Karim MA, Samyn DR, Mattie S, et al. (2017) Distinct features of multivesicular body-lysosome fusion revealed by a new cell-free content-mixing assay. Traffic (Copenhagen, Denmark)
McNally EK, Karim MA, Brett CL. (2016) Selective Lysosomal Transporter Degradation by Organelle Membrane Fusion. Developmental Cell
McNally SM, Karim EK, Vali MA, et al. (2016) How and Why Intralumenal Membrane Fragments Form During Vacuolar Lysosome Fusion. Molecular Biology of the Cell
Bögershausen N, Shahrzad N, Chong JX, et al. (2013) Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. American Journal of Human Genetics. 93: 181-90
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