Sriram Krishnaswamy
Affiliations: | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Blood coagulation, hemostasisGoogle:
"Sriram Krishnaswamy"Mean distance: 10.62 | S | N | B | C | P |
Parents
Sign in to add mentorJohn Kent Bryan | grad student | 1979-1984 | Syracuse |
Kenneth G. Mann | post-doc | 1984-1987 | Univ. of Vermont College of Medicine |
Children
Sign in to add traineeKenneth A. Field | research assistant | University of Vermont | |
Gregory D. Russell | research assistant | University of Vermont | |
Randall K. Walker | grad student | University of Vermont | |
Robert J. Baugh | post-doc | Emory | |
Andreas G. Betz | post-doc | Emory | |
Danilo S. Boskovic | post-doc | Penn | |
Sai Kumar Buddai | post-doc | Penn | |
Parvathi G. Kamath | post-doc | Penn | |
Matthias Wilkens | post-doc | Penn |
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Publications
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Soule EE, Yu H, Olson L, et al. (2022) Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples. Cell Chemical Biology |
Basavaraj MG, Krishnaswamy S. (2020) Exosite binding drives substrate affinity for the activation of coagulation factor X by the intrinsic Xase complex. The Journal of Biological Chemistry |
Cines DB, Zaitsev S, Rauova L, et al. (2020) FcRn augments induction of tissue factor activity by IgG-containing immune complexes. Blood |
Bradford HN, Krishnaswamy S. (2018) Occlusion of anion binding exosite 2 in meizothrombin explains its impaired ability to activate factor V. The Journal of Biological Chemistry |
Gunaratne R, Kumar S, Frederiksen JW, et al. (2018) Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass. Nature Biotechnology |
Bunce M, Chintala M, Krishnaswamy S, et al. (2018) JNJ-64179375 Inhibits Exosite I-Mediated Thrombin Activity While Preserving Exosite II and Active Site Function in Vitro Blood. 132: 24-24 |
Kamikubo Y, Mendolicchio GL, Zampolli A, et al. (2017) Selective factor VIII activation by the tissue factor-factor VIIa-factor Xa complex. Blood |
Bradford HN, Krishnaswamy S. (2016) The Fragment 1 Region of Prothrombin Facilitates the Favored Binding of Fragment 12 to Zymogen and Enforces Zymogen-like Character in the Proteinase. The Journal of Biological Chemistry |
Kumar S, Deng W, Stayrook S, et al. (2016) Structural Basis for the Procofactor to Cofactor Transition in Human Factor V Blood. 128: 253-253 |
Krishnaswamy S. (2015) FVIII-VWF dos-à-dos. Blood. 126: 923-4 |