Tycho H. Heimbach, Ph.D.

Affiliations: 
2003 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Pharmacy, Pharmaceutical Chemistry
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Gordon L. Flynn grad student 2003 University of Michigan
 (Oral phosphate prodrugs: Absorption rate limit considerations.)
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Publications

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Pepin X, Arora S, Borges L, et al. (2024) Parameterization of Physiologically Based Biopharmaceutics Models: Workshop Summary Report. Molecular Pharmaceutics
Wang M, Heimbach T, Zhu W, et al. (2024) Physiologically Based Biopharmaceutics Modeling for Gefapixant IR Formulation Development and Defining the Bioequivalence Dissolution Safe Space. The Aaps Journal. 26: 69
Wu D, Liu J, Paragas EM, et al. (2024) Assessing and mitigating pH-mediated DDI risks in drug development - formulation approaches and clinical considerations. Drug Metabolism Reviews. 1-20
Mackie C, Arora S, Seo P, et al. (2024) Physiologically Based Biopharmaceutics Modeling (PBBM): Best Practices for Drug Product Quality, Regulatory and Industry Perspectives: 2023 Workshop Summary Report. Molecular Pharmaceutics. 21: 2065-2080
Wu F, Mousa Y, Jereb R, et al. (2024) Using Mechanistic Modeling Approaches to Support Bioequivalence Assessments for Oral Products. The Aaps Journal. 26: 19
Tsakalozou E, Mohamed MF, Polak S, et al. (2023) Applications of Modeling and Simulation Approaches in Support of Drug Product Development of Oral Dosage Forms and Locally Acting Drug Products: a Symposium Summary. The Aaps Journal. 25: 96
Bauer A, Berben P, Chakravarthi SS, et al. (2023) Current State and Opportunities with Long-acting Injectables: Industry Perspectives from the Innovation and Quality Consortium "Long-Acting Injectables" Working Group. Pharmaceutical Research
Wu F, Mousa Y, Raines K, et al. (2022) Regulatory Utility of Physiologically Based Pharmacokinetic Modeling to Support Alternative Bioequivalence Approaches and Risk Assessment: A Workshop Summary Report. Cpt: Pharmacometrics & Systems Pharmacology
Wu D, Sanghavi M, Kollipara S, et al. (2022) Physiologically Based Pharmacokinetics Modeling in Biopharmaceutics: Case Studies for Establishing the Bioequivalence Safe Space for Innovator and Generic Drugs. Pharmaceutical Research
Lin W, Chen Y, Unadkat JD, et al. (2022) Applications, Challenges, and Outlook for PBPK Modeling and Simulation: A Regulatory, Industrial and Academic Perspective. Pharmaceutical Research
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