Mark Overhand

Affiliations: 
Leiden University, Leiden, Netherlands 
Area:
Bio-organic Synthesis
Website:
http://biosyn.lic.leidenuniv.nl/people/overhand
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"Mark Overhand"
Mean distance: 8.06
 

Parents

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Sidney M. Hecht grad student 1994 UVA
 (The synthesis of DNA damaging and tumor imaging agents)
Dieter Seebach post-doc 1995-1996 ETH Zürich
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Publications

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Swierstra J, Kapoerchan V, Knijnenburg A, et al. (2016) Structure, toxicity and antibiotic activity of gramicidin S and derivatives European Journal of Clinical Microbiology and Infectious Diseases. 1-7
Cavalli S, Overhand M, Kros A. (2014) Assembly into β-Sheet Structures upon Peptide-Liposome Conjugation through Copper(I)-Catalyzed [3+2] Azide-Alkyne Cycloaddition. Chempluschem. 79: 564-568
Luo J, Otero JM, Yu CH, et al. (2013) Inhibiting and reversing amyloid-β peptide (1-40) fibril formation with gramicidin S and engineered analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 17338-48
Risseeuw M, Overhand M, Fleet GW, et al. (2013) A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues. Amino Acids. 45: 613-89
Guisado-Barrios G, Muñoz BK, Kamer PC, et al. (2013) Cyclic decapeptide gramicidin S derivatives containing phosphines: novel ligands for asymmetric catalysis. Dalton Transactions (Cambridge, England : 2003). 42: 1973-8
Otero JM, Van Der Knaap M, Llamas-Saiz AL, et al. (2013) Design, synthesis, and structural analysis of turn modified cyclo-(αβ3αβ2α)2 peptide derivatives toward crystalline hexagon-shaped cationic nanochannel assemblies Crystal Growth and Design. 13: 4355-4367
van der Knaap M, Basalan F, van de Mei HC, et al. (2012) Synthesis and biological evaluation of gramicidin S-inspired cyclic mixed α/β-peptides. Chemistry & Biodiversity. 9: 2494-506
Li J, Girard G, Florea BI, et al. (2012) Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach. Organic & Biomolecular Chemistry. 10: 8677-83
Kapoerchan VV, Knijnenburg AD, Keizer P, et al. (2012) 'Inverted' analogs of the antibiotic gramicidin S with an improved biological profile. Bioorganic & Medicinal Chemistry. 20: 6059-62
Van Der Knaap M, Otero JM, Llamas-Saiz A, et al. (2012) Design, synthesis and structural analysis of mixed α/β-peptides that adopt stable cyclic hairpin-like conformations Tetrahedron. 68: 2391-2400
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