Helen H. Usansky, Ph.D.
Affiliations: | 2005 | Rutgers University, New Brunswick, New Brunswick, NJ, United States |
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Sign in to add mentorPatrick J. Sinko | grad student | 2005 | Rutgers, New Brunswick | |
(Assessing the influence of Pgp, Mrp2 and CYP3A modulation on oral drug absorption.) |
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Publications
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Usansky HH, Hu P, Sinko PJ. (2008) Differential roles of P-glycoprotein, multidrug resistance-associated protein 2, and CYP3A on saquinavir oral absorption in Sprague-Dawley rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 863-9 |
Usansky HH, Sinko PJ. (2005) Estimating human drug oral absorption kinetics from Caco-2 permeability using an absorption-disposition model: model development and evaluation and derivation of analytical solutions for k(a) and F(a). The Journal of Pharmacology and Experimental Therapeutics. 314: 391-9 |
Sinko PJ, Kunta JR, Usansky HH, et al. (2004) Differentiation of gut and hepatic first pass metabolism and secretion of saquinavir in ported rabbits. The Journal of Pharmacology and Experimental Therapeutics. 310: 359-66 |
Usansky HH, Sinko PJ. (2003) Computation of log BB values for compounds transported through carrier-mediated mechanisms using in vitro permeability data from brain microvessel endothelial cell (BMEC) monolayers. Pharmaceutical Research. 20: 390-6 |