Richard F. Borch, M.D., Ph.D.
Affiliations: | Purdue University, West Lafayette, IN, United States |
Area:
Anticancer Drugs: Design, Synthesis, and Mechanisms of ActionWebsite:
http://www.mcmp.purdue.edu/faculty/?uid=rickbGoogle:
"Richard F. Borch"Bio:
http://www.chem.umn.edu/alumni/IndFacPages/Borch.html
Mean distance: 7.49 | S | N | B | C | P |
Parents
Sign in to add mentorGilbert Stork | grad student | 1965 | Columbia | |
(A synthesis of cis-jasmone. An approach to the synthesis of vitamin B12) |
Children
Sign in to add traineeCaren L Freel Meyers | grad student | ||
Thomas J. Montine | grad student | Rochester (Neurotree) | |
Stan Raucher | grad student | ||
Peter Dedon | grad student | 1982- | UMN |
Liping H. Pettus | grad student | 1993-1995 | University of Rochester Medical Center |
Hugo Garrido Hernandez | grad student | 2001 | Purdue |
Marcy Hernick | grad student | 2002 | Purdue |
Melissa D. Zolodz | grad student | 2003 | Purdue |
Rong Huang | grad student | 2001-2006 | Purdue |
Rodney Nyland | grad student | 2003-2007 | |
Christine Marian | grad student | 2013 | Purdue |
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Publications
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Huang R, Oh H, Arrendale A, et al. (2013) Intracellular targets for a phosphotyrosine peptidomimetic include the mitotic kinesin, MCAK. Biochemical Pharmacology. 86: 597-611 |
Arrendale A, Kim K, Choi JY, et al. (2012) Synthesis of a phosphoserine mimetic prodrug with potent 14-3-3 protein inhibitory activity. Chemistry & Biology. 19: 764-71 |
Marian C, Huang R, Borch RF. (2011) Design and synthesis of a potential SH2 domain inhibitor bearing a stereodiversified 1,4-cis-enediol scaffold. Tetrahedron. 67: 10216-10221 |
Kelley MR, Luo M, Reed A, et al. (2011) Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1. Antioxidants & Redox Signaling. 14: 1387-401 |
Arrendale AA, Huang R, Geahlen R, et al. (2011) Abstract B184: Design, synthesis, and evaluation of novel mitotic centromere-associated kinesin (MCAK) inhibitors. Molecular Cancer Therapeutics. 10 |
Arrendale AA, Kim K, Geahlen R, et al. (2011) Abstract A124: Synthesis of a phosphoserine mimetic prodrug with potent 14-3-3 protein inhibitory activity. Molecular Cancer Therapeutics. 10 |
Nyland RL, Luo M, Kelley MR, et al. (2010) Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1). Journal of Medicinal Chemistry. 53: 1200-10 |
Luo M, Delaplane S, Jiang A, et al. (2008) Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1. Antioxidants & Redox Signaling. 10: 1853-67 |
Wu W, Borch RF. (2006) Synthesis and biological activity of N-2,3-dihydroxypropyl-N-4-chlorobutyl nucleoside phosphoramidate prodrugs. Molecular Pharmaceutics. 3: 451-6 |
Dilworth JT, Kraniak JM, Wojtkowiak JW, et al. (2006) Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1. Biochemical Pharmacology. 72: 1485-92 |